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Titlebook: Structure—Activity Relationships in Environmental Sciences; Monika Nendza Book 1998 Springer Science+Business Media Dordrecht 1998 chemica

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發(fā)表于 2025-3-21 18:50:42 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱Structure—Activity Relationships in Environmental Sciences
編輯Monika Nendza
視頻videohttp://file.papertrans.cn/881/880366/880366.mp4
叢書(shū)名稱Chapman & Hall Ecotoxicology Series
圖書(shū)封面Titlebook: Structure—Activity Relationships in Environmental Sciences; Monika Nendza Book 1998 Springer Science+Business Media Dordrecht 1998 chemica
描述.Structure-Activity Relationships in Environmental Science.is the first book of its kind that brings together information from avariety of sources into one document. It provides a comprehensiveoverview of the entire field of quantitative structure-activityrelationships (QSARs) as well as being a reference for SAR experts..The book comprises three parts. Part One covers the theoreticalbackground of structure-activity studies and Part Two deals with thepractical applications of such methods in the environmental sciences.Part Three critically discusses SAR models with respect to theirreliability and their aptness in environmental hazard and riskassessment. Recommendations are made as to which model to use and thecase is presented for using QSARs in hazard assessment. .The use of QSARs is becoming increasingly important since there islittle experimental data available on environmentally relevantchemicals. .Structure-Activity Relationships in EnvironmentalSciences. will thus serve as an invaluable guide to bothpostgraduate and research scientists as well as professionalecologists.
出版日期Book 1998
關(guān)鍵詞chemical structure; environment; environmental science; environmental sciences; research; risk assessment
版次1
doihttps://doi.org/10.1007/978-1-4615-5805-7
isbn_softcover978-1-4613-7660-6
isbn_ebook978-1-4615-5805-7
copyrightSpringer Science+Business Media Dordrecht 1998
The information of publication is updating

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發(fā)表于 2025-3-21 23:37:33 | 只看該作者
Effects-related parameters the effects of contaminants are ignored. However, the intention of single-species testing is not to simulate all interacting processes of ecotoxicological relevance in ecosystems, but merely to provide indicators of potential hazards.
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Descriptors of the chemical structuresleading to a particular property (i.e. hydrophobic, polar, electrostatic and steric interactions). Preferably, they should reflect the rate-limiting processes that are involved in producing the activity investigated. More than 200 different parameters have been reported (Dearden, 1990).
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發(fā)表于 2025-3-22 10:50:17 | 只看該作者
Activity and effects parametersous ones. The statement by Paracelsus that ‘sola dosis facit venenum’ still holds true (Ariens, Mutschler and Simonis, 1978); any substance, xenobiotic or biogenetic, will be toxic if applied in a sufficiently high dose.
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發(fā)表于 2025-3-22 14:38:22 | 只看該作者
Exposure-related parametersation of the contaminants. The key step in exposure assessment is the use of transport and transformation models to quantify the movement of contaminants from the source through the environment to the target populations.
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發(fā)表于 2025-3-23 06:44:16 | 只看該作者
Exposure-related parametersThe respective parameters required for environmental hazard assessments relate to the spatial and temporal abundance of the contaminants in the various compartments of the ecosystem and hence their bioavailability. Reference environmental descriptions must include the biota exposed to the released c
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