Titlebook: Stem Cells and Cancer Stem Cells, Volume 8; Therapeutic Applicat M.A. Hayat Book 2012 Springer Science+Business Media Dordrecht 2012 Reprog

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Reprogramming and Pluripotency of Epiblast Stem Cellsells can be derived, both being pluripotent: embryonic stem cells (ESCs) are derived from the pluripotent cells in the inner cell mass of the blastocyst, whereas epiblast stem cells (EpiSCs) are derived from the post-implantation late epiblast, at the time of gastrulation. These two types of stem ce

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Epigenetic Modifiers and Stem Cell Differentiationd. Epigenetics is well known to control gene expression and changes of the epigenetic status during differentiation were reported. Epigenetic modifiers are chemical agents that can remove the epigenetic silencing markings and consequently activate the affected genes. The role of the epigenetic modif

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Enrichment and Selection of Stem Cell-Derived Tissue-Specific Precursorse therapies. They also provide an opportunity to study the development of human tissues .. To date, numerous hESC lines have been developed and characterized. In this chapter, we will review the strategies used to direct tissue-specific differentiation of embryonic stem cells. We also will discuss h

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2215-0994 points of view on a specific controversial aspect of cancerItismyhopethatsubsequentvolumesof the serieswilljointhisvolumeinassisting inthemore complete understanding of the causes, diagnosis, and cell-based treatment of major human diseases and debilitating tissue/organ injuries. There exists a tre

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The Role of Bone Marrow-Derived Progenitor Cells in Tumor Growth and Angiogenesiskey pathways controlling communication between tumors and bone marrow-derived pro-inflammatory cells will improve our understanding of vascular dysfunction in tumors and contribute to the identification of new therapeutic targets for anti-angiogenesis strategies.

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Regulation of Self-Renewal and Pluripotency of Embryonic Stem Cells: Role of Natriuretic Peptide Rec(NPR-A), a specific receptor for atrial and brain natriuretic peptide (ANP and BNP), is expressed in preimplantation embryos and in ES cells, and is functional in ES cells. In this chapter, we will provide an overview on the importance of identifying the expression and function of NPR-A in maintaining ES cell characteristics.