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Titlebook: Specificity, Function, and Development of NK Cells; NK Cells: The Effect Klas K?rre,Marco Colonna Book 1998 The Editor(s) (if applicable) a

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發(fā)表于 2025-3-21 16:27:36 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Specificity, Function, and Development of NK Cells
副標題NK Cells: The Effect
編輯Klas K?rre,Marco Colonna
視頻videohttp://file.papertrans.cn/874/873788/873788.mp4
概述Presents recent advances on the function of natural killer cells
叢書名稱Current Topics in Microbiology and Immunology
圖書封面Titlebook: Specificity, Function, and Development of NK Cells; NK Cells: The Effect Klas K?rre,Marco Colonna Book 1998 The Editor(s) (if applicable) a
描述Our understanding of the function of natural killer (NK) cells has dramatically changed in recent years. The discovery of NK receptors specific for MHC class I molecules, and the study of the role of co-stimulatory and adhesion molecules have led to an understanding of how NK cells recognize tumor and virally infected cells that have lost expression of MHC class I molecules or have altered distribution of normal cell surface molecules. Such recognition events lead to intracellular signals which can be either stimulatory or inhibitory. This book provides an insight into how NK cells develop, how they learn to distinguish altered cells from normal cells, and into their biological role in controlling infections and tumors.
出版日期Book 1998
關鍵詞Infektion; Krebs; Krebstherapie; MHC; NK cells; cancer; cancer therapy; cell; cytotoxicity; infection; inhibit
版次1
doihttps://doi.org/10.1007/978-3-642-46859-9
isbn_softcover978-3-642-46861-2
isbn_ebook978-3-642-46859-9Series ISSN 0070-217X Series E-ISSN 2196-9965
issn_series 0070-217X
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
The information of publication is updating

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978-3-642-46861-2The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
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發(fā)表于 2025-3-22 02:04:41 | 只看該作者
Specificity, Function, and Development of NK Cells978-3-642-46859-9Series ISSN 0070-217X Series E-ISSN 2196-9965
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Current Topics in Microbiology and Immunologyhttp://image.papertrans.cn/s/image/873788.jpg
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https://doi.org/10.1007/978-3-642-46859-9Infektion; Krebs; Krebstherapie; MHC; NK cells; cancer; cancer therapy; cell; cytotoxicity; infection; inhibit
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Regulation of Mouse NK Cells by Structurally Divergent Inhibitory Receptorsod. However, from parallel studies in rodents and humans it is becoming increasingly evident that a major mode of NK cell specificity is through regulation of NK cell activation by a series of inhibitory receptors specific for MHC class I molecules.
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Book 1998C class I molecules, and the study of the role of co-stimulatory and adhesion molecules have led to an understanding of how NK cells recognize tumor and virally infected cells that have lost expression of MHC class I molecules or have altered distribution of normal cell surface molecules. Such recog
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Killer Cell Inhibitory Receptor Expression by T Cellsss I ligands can modulate T cell function in a manner comparable to that observed for NK cells. This contribution summarizes recent advances in understanding the functional significance of T cell expression of KIR family members.
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