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Titlebook: Smart STEM-Driven Computer Science Education; Theory, Methodology Vytautas ?tuikys,Renata Burbait? Book 2018 Springer International Publis

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31#
發(fā)表于 2025-3-26 22:54:16 | 只看該作者
Vytautas ?tuikys,Renata Burbait?..Multiple oral anti-angiogenic compounds have been evaluated in NSCLC, both in first-line therapy, or upon disease progression. The majority of agents have shown some evidence of activity, but none have clearly demonstrated improvements in overall survival. Increased toxicities have been observed,
32#
發(fā)表于 2025-3-27 04:52:52 | 只看該作者
33#
發(fā)表于 2025-3-27 08:46:19 | 只看該作者
Vytautas ?tuikys,Renata Burbait?evaluated in SCLC and many studies of these strategies are on-going. Perhaps the most promising approaches involve agents targeting cancer stem cell pathways and immunomodulatory drugs that interfere with the PD1 and CTLA-4 pathways. SCLC offers many barriers to the development of successful therapy
34#
發(fā)表于 2025-3-27 13:12:11 | 只看該作者
ABCG2, and Nanog. Yet another cell type that is also associated with increased resistance to treatment is epithelial-to-mesenchymal transition (EMT) phenotypic cells. Through the processes of EMT, epithelial cells lose their epithelial phenotype and gain mesenchymal properties, rendering EMT phenoty
35#
發(fā)表于 2025-3-27 14:44:47 | 只看該作者
Vytautas ?tuikys,Renata Burbait?erable progress in understanding of the clinical behaviour of lung cancer thereby establishing the importance of distinguishing between the major histologic types. Thera- peutic advancement was particularly experienced in small cell carcinoma with the introduction of combination chemotherapy after t
36#
發(fā)表于 2025-3-27 21:33:50 | 只看該作者
37#
發(fā)表于 2025-3-27 22:07:41 | 只看該作者
Vytautas ?tuikys,Renata Burbait?blood vessels (i.e. arteries, arterioles, venules, and veins) from these initial vessels involves recruitment of smooth muscle cell (SMC) precursor cells into the region surrounding the endothelial tubes with subsequent morphogenesis of the appropriate blood vessel. This process requires that cells
38#
發(fā)表于 2025-3-28 03:07:24 | 只看該作者
Vytautas ?tuikys,Renata Burbait?ar walls similar to the conditions observed in patients with emphysema and resulting in cystic changes in lobules were also seen in the lungs of patients with long-standing RA. The exact mechanism of peribronchiolar metaplasia with intralobular cystic alteration in the never smokers with RA still re
39#
發(fā)表于 2025-3-28 10:10:50 | 只看該作者
40#
發(fā)表于 2025-3-28 13:51:18 | 只看該作者
Vytautas ?tuikys,Renata Burbait?sing diagnostic tools such as interferon-gamma release assay (IGRA), anti-MAC antibody measurement, and Xpert MTB/rifampin (RIF) assay are newly available. Further research is needed to verify these assays. As a rule, to avoid development of drug-resistant strains, treatment with multiple drugs for
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