Titlebook: Single-molecule Studies of Proteins; Andres F. Oberhauser Book 2013 Springer Science+Business Media New York 2013

LAIR

Intuitive

丑惡

Nanomechanics of Proteins, Both Folded and Disordered, of proteins, which has recently opened the new, exciting and fast-growing research field of protein nanomechanics. The aim of this review is to describe the principles of this methodology and to discuss the main achievements in this field, with special emphasis on its emerging application to the analysis of intrinsically disordered proteins.

注意

,AFM Visualization of Protein–DNA Interactions,are limited to SSB protein and chromatin. Special attention is given to time-lapse AFM imaging in aqueous solutions that enables direct observation of protein–DNA dynamics and interactions. A few examples of the application of time-lapse high-speed AFM are provided as well.

compose

CUMB

Book 2013ed at established investigators and post-doctoral researchers in the life sciences wanting to pursue research in the various areas in which single-molecule approaches are important; this volume also remains accessible to advanced graduate students seeking similar research goals.

辯論的終結

Book 2013gical events, such as the imaging and mapping of cell surface receptors, the analysis of the unfolding and folding pathways of single proteins, the analysis interaction forces between biomolecules, the study of enzyme catalysis or the visualization of molecular motors in action. The chapters are aim

精致

壓碎

Nanomechanics of Proteins, Both Folded and Disordered,s important biological questions in key areas of cell biology (e.g., cell adhesion and signaling, neurodegeneration) and protein science (e.g., protein folding, protein structure and stability, catalysis, protein evolution, conformational polymorphism, and amyloidogenesis). One of these techniques,

Liability

Force Spectroscopy and Recognition Imaging of Cells from the Immune System,lymphocytes that secrete large amounts of cytokines, interferon, and tumor-necrosis factor upon recognition of endogenous and exogenous agonists such as CD1d-bound lipid molecules. Single-molecule force spectroscopy has been applied for the investigation of affinity of the iNKT T cell Receptor (TCR)