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Titlebook: Rubidomycin; A New Agent against J. Bernard,R. Paul,R. Maral Book 1969 Springer-Verlag Berlin Heidelberg 1969 alkaloids.antibiotics.cancer

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樓主: COAX
21#
發(fā)表于 2025-3-25 05:30:29 | 只看該作者
Structurear to those of the 1,4,5-trihydroxyanthraquinones. It shows, in methanol solution, the following absorption peaks: E. = 665, λ = 234 mμ; E. = 462, λ = 252 mμ; E. = 153, λ = 290 mμ; E. = 214, λ = 480 mμ; E. = 218, λ = 495 mμ; E. = 112, λ = 532mμ. The indicator-like behaviour, the metal complexing pro
22#
發(fā)表于 2025-3-25 08:10:25 | 只看該作者
Acute Granulocytic Leukemia Acute Myeloblastic and Promyelocytic Leukemiavery slow [91]. Up to 1960 the percentage of complete remissions with purine and folic acid antagonists did not exceed 12% in a series of 118 cases observed between 1956 and 1960 [23, 24]. The situation improved a little with methyl-GAG [19] and then with cytosine arabinoside; but the rate for compl
23#
發(fā)表于 2025-3-25 12:57:36 | 只看該作者
24#
發(fā)表于 2025-3-25 18:17:19 | 只看該作者
25#
發(fā)表于 2025-3-25 22:53:22 | 只看該作者
Treatment of Chronic Leukemia, Sarcoma, Hodgkin’s Disease, and Cancer with Rubidomycinydroxyurea, can bring about good remissions in chronic myeloid leukemia. There are thus two important questions to answer in relation to the use of rubidomycin as a therapeutic agent: 1. can it bring about remission in this condition? and 2. what advantages does it have over the drugs already known?
26#
發(fā)表于 2025-3-26 02:24:14 | 只看該作者
Acute Granulocytic Leukemia Acute Myeloblastic and Promyelocytic Leukemia9, 35], and 43% with the combination of 6-mercaptopurine, cytosine arabinoside, methyl-GAG, and prednisone (32 cases) [230]. Rubidomycin was the first drug that, when used alone, gave a percentage of complete remissions slightly above 50% (in a matching series of 64 cases) [36] (Table 37).
27#
發(fā)表于 2025-3-26 05:47:11 | 只看該作者
28#
發(fā)表于 2025-3-26 09:26:00 | 只看該作者
29#
發(fā)表于 2025-3-26 16:21:12 | 只看該作者
J. Bernard,R. Paul,M. Boiron,Cl. Jacquillat,R. MaralPariser Prinzipien und die Globale Allianz Nationaler Menschenrechtsinstitutionen, das R?mische Statut und der Internationale Strafgerichtshof genannt. Auch die global ausgerichteten siebzehn ?Ziele für nachhaltige Entwicklung“ (?Sustainable Development Goals“) der Vereinten Nationen, die einen Akti
30#
發(fā)表于 2025-3-26 17:13:47 | 只看該作者
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