| 書目名稱 | Rodent Models of Stroke | | 編輯 | Ulrich Dirnagl | | 視頻video | http://file.papertrans.cn/832/831469/831469.mp4 | | 概述 | Provides hands-on guidance to most relevant stroke models in rodents.Comprehensive guide to non-invasive imaging in rodent stroke research (MRI, optical, nuclear medicine).Covers all relevant techniqu | | 叢書名稱 | Neuromethods | | 圖書封面 |  | | 描述 | In view of the numerous failures of clinical trials aimed at improving stroke therapy, the role and potential benefit of experimentally modeling focal cerebral ischemia in rodents has been debated. When methods of systematic review and metaanalyis are applied, however, it turns out that experimental models actually faithfully predicted the negative outcomes of clinical trials. In addition, thrombolysis and neuroprotection by hypothermia, first described in animal models, are key examples of treatment modalities that have made it successfully into clinical practice. In Rodent Models of Stroke, an international consortium of authors aims at critically addressing the issues on a very practical level, from choosing the model and outcome measures, designing the experiment, conducting and analyzing it, to reporting it in a scientific publication. The structure and content of the book reflect both the authors’ longstanding expertise in experimental and clinical stroke research and their roles in training the scientific community in the tools of the trade. As a volume in the successful Neuromethods series, the chapters provide authoritative reviews of the most commonly used, well-honed app | | 出版日期 | Book 2010 | | 關(guān)鍵詞 | Brain and spinal cord injury; Focal cerebral ischemia; Neurological injury; Neuroprotection; Stroke mode | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-60761-750-1 | | isbn_softcover | 978-1-4939-5807-8 | | isbn_ebook | 978-1-60761-750-1Series ISSN 0893-2336 Series E-ISSN 1940-6045 | | issn_series | 0893-2336 | | copyright | Springer Science + Business Media, LLC 2010 |
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