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Titlebook: Riboswitches; Methods and Protocol Alexander Serganov Book 2009 The Editor(s) (if applicable) and The Author(s), under exclusive license to

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,Application of Fluorescent Measurements for Characterization of Riboswitch–Ligand Interactions,ow specific examples in which 2AP fluorescence can be used to monitor structural changes in the aptamer domain of the S-adenosyl methionine (SAM) riboswitch and where it can be used as a ligand for the guanine riboswitch.
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RNA-Dependent RNA Switches in Bacteria,get mRNA. Systems of this type are widespread in bacteria, and they fall into several classes based on the type of RNA that acts as the regulator, and the mode of interaction of the regulatory RNA with its target. These include systems in which the regulatory RNA is encoded on the opposite strand of
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1064-3745 n many regulatory circuits. Such a viewpoint received strong support several years ago after the discovery of riboswitches and related RNA sensors – mRNA regions capable of alternating their conformations in re978-1-61737-947-5978-1-59745-558-9Series ISSN 1064-3745 Series E-ISSN 1940-6029
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