Titlebook: RibosomesStructure, Function, and Dynamics; Marina V. Rodnina,Wolfgang Wintermeyer,Rachel Gree Book 2011 Springer-Verlag GmbH Wien 2011 ge

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DNR215

Modifications of ribosomal RNA: From enzymes to functionoduce the majority of their rRNA modifications (Decatur and Fournier, 2002). By contrast, bacteria have developed specific enzymes for each one of the (fewer) modifications they have. Nevertheless, there are many different rRNA modifications in bacteria. Despite intensive study for several decades,

Dappled

Translation initiation at the root of the cold-shock translational biasroteins synthesized during cold adaptation and in cold-adapted cells are: (i) to deal with unfavorable secondary structures of nucleic acids induced/stabilized by the cold, which are expected to hinder basic functions such as transcription, ribosome assembly, and translation; (ii) to oppose the cold

dry-eye

Recruiting knotty partners: The roles of translation initiation factors in mRNA recruitment to the ef the mRNA that, through a number of protein-protein interactions, brings the ribosome to the very beginning of the mRNA. Protein factors are also thought to be responsible for removing secondary structure and RNA binding proteins from the RNA to create a single-stranded region for the ribosome to b

慢跑

Nucleate

Mechanisms of decoding and peptide bond formation the nascent peptide chain by one amino acid. The functional centers of the ribosomes are composed mostly of rRNA. Thus, understanding decoding and peptide bond formation requires answers to several fundamental questions: (i) how does the rRNA machinery recognize tRNAs and mRNAs? (ii) how does the r

Misnomer

Book 2011thin, and emerging from, the ribosomal peptide exit tunnel are addressed in several articles. Structural and single-molecule studies reveal a picture of the ribosome exhibiting the energy landscape of a processive Brownian machine. The collection provides up-to-date reviews which will serve as a sou

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Steven T. Gregory,Hasan Demirci,Jennifer F. Carr,Riccardo Belardinelli,Jill R. Thompson,Dale Cameron