| 書目名稱 | Rheumatoid Arthritis | | 副標題 | Recent Research Adva | | 編輯 | Josef S. Smolen,Joachim R. Kalden,Ravinder N. Main | | 視頻video | http://file.papertrans.cn/831/830092/830092.mp4 | | 圖書封面 |  | | 描述 | Many advances have occurred in the last 5 years especiallyin understanding genetic susceptibility factors, the role ofimmune response in chronicarthritis and the relationshipbetween cellular processes that underlie inflammation andtissue damage. All these are dealt with in depth intheindividual contributions.Genetics studies included illustrate howstudies of HLAgenes and genes controlling the autoantibody repertoiremaybe involved. Environmental factors are believed to beimportant and studies both in humans and in experimentalmodels on the role of viral andbacterial agents arecovered. The fascinating relationship betweenmicrobes,dysregulated immune responses and oncogenes are alsoexamined.Since autoimmunity is the key aspect of theimmunologicalresponse in rheumatoid arthritis, the role of antigensisre-examined as is the part played by immune T and B cells.New areas of clinical application of basic science is wellpresented in this book, forexample, in examining howmarkers of cartilage destruction may become important inmonitoring disease activity. A chapter reviewing possiblefuture novel therapies is included. | | 出版日期 | Conference proceedings 1992 | | 關鍵詞 | Arthritis; Immungenetik; antibody; antigen; autoimmunity; bacteria; cartilage; genetics; immune response; imm | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-642-76189-8 | | isbn_softcover | 978-3-642-76191-1 | | isbn_ebook | 978-3-642-76189-8 | | copyright | Springer-Verlag Berlin Heidelberg 1992 |
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