Titlebook: Revising Oral Pharmacokinetics, Bioavailability and Bioequivalence Based on the Finite Absorption Ti; Panos Macheras,Athanasios A. Tsekour

甜食

Bioavailability Under the Prism of Finite Absorption Timebed in terms of FAT. Explicit relationships are derived for the bioavailable fraction as a function of the model parameters assuming one-compartment model disposition with zero- or first-order absorption lasting for a certain period of time. An application using a theophylline example is presented. Extent and rate metrics are reinterpreted.

反叛者

Bioequivalence Under the Prism of Finite Absorption Timetric for the extent of drug absorption. This concept was successfully applied to two published bioavailability digoxin studies. The cumulative ratio of areas as a function of sampling time is suggested as a diagnostic test and criterion for the assessment of the drug’s extent of absorption.

值得贊賞

bronchiole

Deduct

Sputum

Lipoma

疼死我了

978-3-031-20027-4The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl

不自然

Revising Oral Pharmacokinetics, Bioavailability and Bioequivalence Based on the Finite Absorption Ti

圓柱

Revising Oral Pharmacokinetics, Bioavailability and Bioequivalence Based on the Finite Absorption Ti978-3-031-20025-0