Titlebook: Reviews of Physiology, Biochemistry and Pharmacology; Stine Helene Falsig Pedersen Book 2021 The Editor(s) (if applicable) and The Author(

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Reviews of Physiology, Biochemistry and Pharmacology978-3-030-74289-8Series ISSN 0303-4240 Series E-ISSN 1617-5786

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Reviews of Physiology, Biochemistry and Pharmacologyhttp://image.papertrans.cn/r/image/829670.jpg

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Book 2021Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.?.

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https://doi.org/10.1007/978-3-030-74289-8Rheumatoid Arthritis; Diabetic Kidney Disease; Phosphate Homeostasis; Mast Cell Activation; Organoids; Si

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Potential of Renin-Angiotensin-Aldosterone System Modulations in Diabetic Kidney Disease: Old Playeor arm (ACE2/angiotensin-(1-7)/Mas receptor axis). These advances have paved the way for the development of new therapies targeting the RAAS for better treatment of DKD. In this review, we aimed to summarise the involvement of the depressor arm of the RAAS in DKD. Moreover, in modern drug discovery

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Ligands and Signaling of Mas-Related G Protein-Coupled Receptor-X2 in Mast Cell Activation,on of cytokines and chemokines via MAPK and NF-κB pathways, resulting in MCs activation. Agonists of MRGPRX2 on MCs are divided into peptides (including antimicrobial peptides, neuropeptides, MC degranulating peptides, peptide hormones) and nonpeptides (including FDA-approved drugs). Inhibitors of M