Titlebook: Respiratory Muscles in Chronic Obstructive Pulmonary Disease; A. Grassino,C. Fracchia,L. Zocchi Conference proceedings 1988 Springer-Verla

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Some old concepts in respiratory muscle mechanicsstotle’s observations, they are of interest more as examples of physiology. After Galen’s remarkable experiment some half a millennium later, there is an unfortunate gap in our knowledge of the great Abbasid isolated examples of Vesalius, Borelli and others, there are no further significant contribu

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Inspiratory muscle physiology, with particular regard to the diaphragms of the two parts of the diaphragm. The co-ordination of these separate activities can be affected by conditions such as experimental liquid substitution of the abdominal viscera (approximating to clinical manifestations of ascites) or hyperinflation. While the respiratory role of the diagram does

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Respiratory muscle physiology with particular regard to rib cage musclesespiratory physiologists..Some investigators have postulated the diaphragm as the sole muscular agent recruited in quiet inspiration. A review of recent studies in dogs and humans challenges this view..The author, on the basis of personal observation of trained human subjects, concludes that diaphra

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Patterns of inspiratory muscle activation with changing levels of ventilatory demandn vagotomized and anaesthetized animals. Findings suggest that the response elicited ultimately depends on the role of the central inspiratory motor control system..In postulating the applicability of such findings to human subjects, the greater recruitment of extra-diaphragmatic than diaphragmatic

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Effect of lung volume on in vivo contraction characteristics of the human diaphragmansdiaphragmatic pressure declined from a mean of 49.1 (SD: 9.1) cm H.O at RV to a mean of 19.6 cm H.O (SD: 5.97) at TLC. Twitch contraction time fell from a mean of 91.8 (SD: 11.3) at RV to a mean of 57.7 ms (SD: 7.4) at TLC. There was a good correlation between changes in contraction time and tran

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Nutritional and metabolic aspects of COPD surprising, should one consider that the understanding of the response of body tissues to blood gas alterations is of utmost importance in order to assess the systemic effects of the disease..The present paper is thus aimed at giving information on cell metabolism derangements in COPD patients with