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Titlebook: Resistance to Targeted Therapies in Breast Cancer; Jenifer R. Prosperi Book 2017 Springer International Publishing AG 2017 Targeted Therap

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發(fā)表于 2025-3-21 19:37:32 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Resistance to Targeted Therapies in Breast Cancer
編輯Jenifer R. Prosperi
視頻videohttp://file.papertrans.cn/829/828461/828461.mp4
概述This book will provide an in-depth description of resistance to targeted therapies in breast cancer.This book will discuss targeted therapies used to treat ER+ or Her2+ breast cancers (i.e. Tamoxifen
叢書名稱Resistance to Targeted Anti-Cancer Therapeutics
圖書封面Titlebook: Resistance to Targeted Therapies in Breast Cancer;  Jenifer R. Prosperi Book 2017 Springer International Publishing AG 2017 Targeted Therap
描述.We present an in-depth description of resistance to targeted therapies in breast cancer. Targeted therapies discussed here include those used to treat ER+ or Her2+ breast cancers (i.e., Tamoxifen or trastuzumab) or those targeting signaling pathways aberrantly activated in triple negative breast cancer (i.e., EGFR and Wnt signaling). We have also provided an overview of standard of care as an introduction into the importance of targeted therapy. It is our hope that this volume gives an insight into the landscape of breast cancer treatment, the challenges of targeted therapy, and a glimpse into the future of breast cancer therapy..
出版日期Book 2017
關(guān)鍵詞Targeted Therapy; Her2-Targeted Therapy; Hormone Therapy; Angiogenesis; EGFR Inhibition
版次1
doihttps://doi.org/10.1007/978-3-319-70142-4
isbn_softcover978-3-319-88891-0
isbn_ebook978-3-319-70142-4Series ISSN 2196-5501 Series E-ISSN 2196-551X
issn_series 2196-5501
copyrightSpringer International Publishing AG 2017
The information of publication is updating

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發(fā)表于 2025-3-22 00:50:20 | 只看該作者
Resistance to HER2-Targeted Therapy,pressed in 20–25% of breast cancers and high expression is associated with poor clinical outcomes if not treated with an HER2-targeted drug. Although HER2 does not have a known extracellular ligand, HER2 is the preferred heterodimerization partner for the other HER-family receptors and HER2-containi
地板
發(fā)表于 2025-3-22 06:16:47 | 只看該作者
Endocrine Resistance and Breast Cancer Stem Cells: The Inflammatory Connection that Could Lead to Nstrogen receptor (ER) and will be treated with endocrine therapy, such as tamoxifen or aromatase inhibitors. Interfering with ER action via endocrine therapies has been a mainstay of breast cancer treatment for more than a century. But despite its proven success, the onset of endocrine resistance li
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發(fā)表于 2025-3-22 09:56:45 | 只看該作者
EGFR Resistance,ll growth by inhibiting epidermal growth factor receptors (EGFRs). Targeting the EGFR has been intensely pursued in the breast cancer, with mixed results and challenges with respect to treatment resistance emerging over time. The resistance to EGFR inhibitors is now well recognized due its high prev
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發(fā)表于 2025-3-22 14:46:30 | 只看該作者
Targeting FGFR for the Treatment of Breast Cancer,f at least 5 distinct subtypes of the disease. Importantly, breast cancer subtyping can predict for tumor recurrence and drives the clinical application of endocrine and human epidermal growth factor receptor 2 (Her2)-targeted therapies. Recent studies have revealed that these subtypes of breast can
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Future Paradigm of Breast Cancer Resistance and Treatment,detecting the disease progression and relapse. Resistance to therapy is not only common but expected. Multidisciplinary joint efforts are required in making necessary progress with breast cancer treatment. With the recent advances in multiplex genotyping and high-throughput genomic sequencing techno
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發(fā)表于 2025-3-23 01:53:03 | 只看該作者
Book 2017ncer (i.e., EGFR and Wnt signaling). We have also provided an overview of standard of care as an introduction into the importance of targeted therapy. It is our hope that this volume gives an insight into the landscape of breast cancer treatment, the challenges of targeted therapy, and a glimpse into the future of breast cancer therapy..
10#
發(fā)表于 2025-3-23 07:04:50 | 只看該作者
Book 2017t ER+ or Her2+ breast cancers (i.e., Tamoxifen or trastuzumab) or those targeting signaling pathways aberrantly activated in triple negative breast cancer (i.e., EGFR and Wnt signaling). We have also provided an overview of standard of care as an introduction into the importance of targeted therapy.
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