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Titlebook: Renal Cell Carcinoma; Molecular Features a Mototsugu Oya Book 2017 Springer Japan KK 2017 Molecular-targeted therapy.TKI.anti-angiogenic ag

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發(fā)表于 2025-3-21 16:14:29 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Renal Cell Carcinoma
副標題Molecular Features a
編輯Mototsugu Oya
視頻videohttp://file.papertrans.cn/827/826987/826987.mp4
概述Provides a comprehensive review of diagnosis and treatments of renal cell carcinoma.Presents the most recent advances in molecular bases and targeted therapy for renal cell carcinoma.Contains importan
圖書封面Titlebook: Renal Cell Carcinoma; Molecular Features a Mototsugu Oya Book 2017 Springer Japan KK 2017 Molecular-targeted therapy.TKI.anti-angiogenic ag
描述.This book provides a comprehensive review of diagnosis and treatments of renal cell carcinoma (RCC) for practitioners and researchers with an interest in this disease. A major aim of the book is to present the most important and most recent advances in molecular bases and targeted therapy for this neoplasm. The remarkable resistance to chemotherapy and radiotherapy and the minimum contribution of cancer genes that commonly mutate in other adult epithelial cancers have made RCC highly distinct from other types of solid neoplasms. In the past decade, however, treatment options for RCC have been expanding and moving quickly toward laboratory-based and molecular-targeted therapies. Advances in RCC therapy also have brought novel treatment options to other types of cancer, such as a TKI for hepatocellular carcinoma and gastrointestinal tumors, as well as mTOR inhibitors to progressive neuroendocrine tumors of pancreatic origin and to breast cancer, suggesting that RCC is no longer an "orphan disease" in the field of molecular oncology. Additional topics covered in the book include pharmacokinetics and pharmacodynamics in molecular-targeted agents and the putative mechanism of resistanc
出版日期Book 2017
關(guān)鍵詞Molecular-targeted therapy; TKI; anti-angiogenic agent; mTOR inhibitors; tyrosine-kinase inhibitors
版次1
doihttps://doi.org/10.1007/978-4-431-55531-5
isbn_softcover978-4-431-56661-8
isbn_ebook978-4-431-55531-5
copyrightSpringer Japan KK 2017
The information of publication is updating

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沙發(fā)
發(fā)表于 2025-3-21 23:50:51 | 只看該作者
板凳
發(fā)表于 2025-3-22 01:39:17 | 只看該作者
Molecular Genetics of Renal Cell Carcinoma,and whole-genome sequencing, the genomic landscapes of renal cell carcinoma (RCC), consisting mainly of clear-cell, papillary (1 and 2), and chromophobe subtypes, have been characterized. This genomic information, coupled with DNA methylation, has shed light on the molecular biology of RCC and creat
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發(fā)表于 2025-3-22 10:42:12 | 只看該作者
Imaging Features of Renal Cell Carcinoma Differential Diagnosis, Staging, and Posttreatment Evaluatection of various subtypes of renal cell carcinomas (RCCs) and benign renal tumors. The differentiation of RCCs from benign tumors such as fat-poor angiomyolipoma and oncocytoma is very important to prevent unnecessary surgery. In addition, the recent progress of therapies to treat RCCs, including n
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發(fā)表于 2025-3-22 19:55:59 | 只看該作者
Natural History and Active Surveillance,is seen in cancers less than 4?cm. Surgery, either radical or partial nephrectomy, has been the mainstay of treatment of a small renal mass (SRM), defined as a usually incidentally discovered renal mass <4?cm in diameter which enhances on contrast imaging. There is morbidity associated with this sta
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發(fā)表于 2025-3-23 00:27:23 | 只看該作者
Surgical Treatment for Renal Cell Carcinoma,f renal cell carcinoma is an integral component of oncologic management. The spectrum of renal cell carcinoma presentation from small renal masses, locally advanced disease, and in the presence of metastasis varies with the surgical armamentarium needed to treat this diverse group of patients. In ge
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發(fā)表于 2025-3-23 08:33:12 | 只看該作者
Tyrosine Kinase Inhibitors: Sorafenib, Sunitinib, Axitinib, and Pazopanib,ant improvement in patient outcomes. To date, targeting the vascular endothelial growth factor receptor (VEGFR) has been shown to lead to improved clinical outcomes in metastatic RCC. Currently, four VEGFR tyrosine kinase inhibitors (TKIs) have been approved by the Food and Drug Administration (FDA)
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