Titlebook: Regulatory T Cells and Clinical Application; Shuiping Jiang Book 2008 Springer-Verlag New York 2008 Asthma.T cell.Transplantation.allergy.

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Bronchial-Tubes

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The Role of IL-2 in the Development and Peripheral Homeostasis of Naturally Occurring CD4,CD25,Foxp3 that IL-2 is important for T. cell suppressive function. Other important issues concern the cellular source of IL-2 and novel aspects that potentially regulate and limit IL-2 to T. cells. Although IL-2 is essential, other cytokines within and outside the γc family likely contribute to T. cell production.

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CD4+CD25+ Regulatory T Cells and TGF-Beta in Mucosal Inflammationferation. Consistently abrogation of Tregs maturation as observed in different systems leads to a phenotype resembling that caused by the impairment of the TGF-beta signaling thus linking Tregs and TGF-beta activities. Here we review data generated in the last years at support of this link.

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