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Titlebook: Regulation of Gene Expression in the Tumor Environment; Regulation of melano Menashe Bar-Eli (Dr) Book 2008 Springer Science+Business Media

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書目名稱Regulation of Gene Expression in the Tumor Environment
副標(biāo)題Regulation of melano
編輯Menashe Bar-Eli (Dr)
視頻videohttp://file.papertrans.cn/826/825676/825676.mp4
概述Describes the contribution of the tumor microenvironment to tumor growth and metastasis.Gives a unique opportunity to understand the cross talk between tumor cells (the seed) and the organ microenviro
叢書名稱The Tumor Microenvironment
圖書封面Titlebook: Regulation of Gene Expression in the Tumor Environment; Regulation of melano Menashe Bar-Eli (Dr) Book 2008 Springer Science+Business Media
描述.It is now becoming very clear that the development and progression of tumor towards the malignant (metastatic) phenotype depends tightly on the interaction between the tumor cells and the tumor microenvironment. Tumor cells respond to stimuli generated within the tumor microenvironment for their growth advantage while the tumor cell themselves reshape and remodel the architecture and function of their extracellular matrices. The term tumor microenvironment is a wide umbrella consisting of stromal cells such as fibroblasts and endothelial cells and infiltration immune cells including T and B cells, macrophages, and other inflammatory cells (PMNs). These different components of the tumor microenvironment could have stimulatory and inhibitory effects on tumor progression by regulating the gene expression repertoire within the tumor cells on one hand and the stroma cells on the other. In this volume we have seven contributors who will discuss several different aspects on the cross talk within the tumor microenvironment components leading to the acquisition of the metastatic phenotype. It is our hope that these state-of-the-art studies will shed further light on our understanding of th
出版日期Book 2008
關(guān)鍵詞Angiogenesis; Invasion; Macrophages; Metastasis; Tumor Growth; Tumor Microenvironment; regulation
版次1
doihttps://doi.org/10.1007/978-1-4020-8341-9
isbn_softcover978-90-481-7849-0
isbn_ebook978-1-4020-8341-9
copyrightSpringer Science+Business Media B.V. 2008
The information of publication is updating

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Gabriel J. Villares,Menashe Bar-Eliture on product- and geographic boundary dynamics, it does not yet present an integrate perspective across all firm scope dimensions, which also include firms‘ vertical boundaries (Chandler, 1962; Andrews, 1971/1987; Porter, 1985). We have observed that vertical scope research has developed along a
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