Titlebook: Reducing Mortality in Critically Ill Patients; Giovanni Landoni,Marta Mucchetti,Rinaldo Bellomo Book 20151st edition Springer Internationa

overhaul

Daily Interruption of Sedatives to Improve Outcomes in Critically Ill Patientshere is growing evidence that a lower exposure to sedative agents, particularly benzodiazepines, improves patients outcome in term of survival and intensive care unit length of stay..A large multicenter randomized controlled trial by Girard and colleagues suggested a significant reduction in long te

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Tight Glycemic Controlesults of the Leuven trials, concerns were raised about the incidence of hypoglycemia and extra-mortality in both surgical and medical patients. Despite a clear physiologic rationale for glucose control in critically ill patients, the best target level of glycemia, particularly for previously non-di

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Hydroxyethyl Starch in Critically Ill Patientsitically ill patients, including renal and hemostatic impairment and increased mortality. The systematic reviews on hydroxyethyl strach in critically ill patients confirm these findings. They also showed that there is no evidence that differences in molecular weight, substitution ratio, trial design

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Growth Hormone in the Critically Ill adequate nutritional support in other patient groups resulted in preserved nitrogen balance. Despite the initial promising results of small trials, the large multicenter randomized controlled trial by Takala and colleagues showed that supranormal growth hormone supplementation in critically ill pat

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Diaspirin Cross-Linked Hemoglobin and Blood Substitutesiers in general, has a reduced risk of transfusion harming effects, universal compatibility, infinite availability and long-term storage capability. Despite initial enthusiasm, the trial by Sloan and colleagues showed an increased risk of death in patients treated with this blood substitute on the t

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Glutamine Supplementation in Critically Ill Patients modulating glucose metabolism and inducing cellular protection pathways. Trials showed conflicting results on mortality. Heyland et al showed a significant increase in mortality in critically ill patients who received glutamine supplementation. Their results were confirmed by a subsequent meta-anal

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Reducing Mortality in Critically Ill Patients: A Systematic Updatetions that showed a significant effect on mortality in adult critically ill patients. We searched PubMed, Medline and EMBASE databases, using the same search strategy and inclusion/exclusion criteria chosen for the original Consensus Conference..Only four papers that fulfill our inclusion criteria w