Titlebook: Recurrent Implantation Failure; Etiologies and Clini Jason M. Franasiak,Richard T. Scott Jr. Book 2018 Springer International Publishing AG

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Embryonic Factors Associated with Recurrent Implantation Failure,ality embryos” fail to implant in a normal uterus following multiple embryo transfers, there is often no immediate obvious reason. Despite considerable improvements in both clinical protocols and laboratory technologies over the last 30?years of assisted reproduction, the question remains as to how

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The Genetics of Pregnancy Failure,enetic factors that contribute to early embryo failure to implant or to miscarry after implantation. Much of our knowledge has been accumulated through analysis of products of conception which reveals that aneuploidy, particularly trisomy, is the leading cause of early pregnancy failure. The role of

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Immune Factors in Recurrent Implantation Failure,e system implication in reproduction were focused on finding markers on peripheral blood and less on uterine environment. Maternofetal tolerance begins at the uterine level, so successful adaptation to the fetus happens after a complicated process. Insufficient invasion of the uterine lining by inva

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Stress and Implantation Failure,rus and endometrium, which are clearly critical to the most important step in reproduction, namely, implantation. Implantation requires that the endometrium become receptive to a healthy blastocyst. Thus, folliculogenesis must result not only in ovulation but also in the secretion of estradiol and p

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Endocrine Causes of Implantation Failure, required for clinicians and investigators attempting to optimize an individual patient’s likelihood of success. Our current level of knowledge is the result of many elegant studies to elucidate these mechanisms. However, our tools for assessing the proper functioning of the endometrium in relation

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Anatomic Abnormalities and Recurrent Implantation Failure,cy outcomes. Treating these conditions improves pregnancy rates and outcomes. Hydrosalpinges reduce IVF pregnancy rates by ~50% by impeding embryo implantation. Treating them prior to IVF by salpingectomy, salpingostomy, or tubal ligation restores the success rates back to normal. This chapter revie

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Psychosocial Implications of Recurrent Implantation Failure,, cognitive, economic, spiritual, and social realms for patients. Keeping pace with developments in reproductive medicine, psychological research regarding infertility and recurrent pregnancy loss has focused on the associated psychosocial factors and the impact of these factors on treatment and out

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