Titlebook: Recent Advances in Tryptophan Research; Tryptophan and Serot Graziella Allegri Filippini,Carlo V. L. Costa,Anto Book 1996 The Editor(s) (if

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The Effect of Low Brain Serotonin on Mood and Aggression in Humansydroxyindoleacetic acid in the cerebrospinal fluid of depressed or aggressive patients (van Praag, 1994) is an association that does not necessarily imply cause, while the ability of antidepressants to potentiate serotonin function (Blier and de Montigny, 1994) may be more relevant to the action of

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Tryptophan and 5-HT in Psychiatric Illnessral administration of a TRP-free amino acid mixture. This procedure leads to a 30 to 50% decrease in brain 5-HT levels in laboratory animals and decreases human plasma TRP levels by 70–80% in 5 hours. TRP depletion alters human behaviour in different ways depending on the gender and clinical status

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Tryptophan Metabolism and Disposition in Relation to Alcohol and Alcoholismfied into those: (1) exerted by acute or chronic alcohol administration and/or subsequent withdrawal; (2) already present in the absence of alcohol consumption, such as in naive alcohol-preferring animals or in abstinent alcoholics. In normal rats, acute ethanol administration activates liver Trp py