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Titlebook: Recent Advances in Transthyretin Evolution, Structure and Biological Functions; Samantha J. Richardson,Vivian Cody Book 2009 Springer-Verl

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發(fā)表于 2025-3-21 16:42:35 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Recent Advances in Transthyretin Evolution, Structure and Biological Functions
編輯Samantha J. Richardson,Vivian Cody
視頻videohttp://file.papertrans.cn/824/823039/823039.mp4
概述Transthyretin is a most exciting example for the study of the evolution of protein structure-function relationships.Covers both the basic and the clinical research into transthyretin.Brings the reader
圖書封面Titlebook: Recent Advances in Transthyretin Evolution, Structure and Biological Functions;  Samantha J. Richardson,Vivian Cody Book 2009 Springer-Verl
描述Since its ?rst description in 1942 in both serum and cerebrospinal ?uid, transthyretin (TTR) has had an eventful history, including changes in name from “prealbumin” to “thyroxine-binding prealbumin” to “transthyretin” as knowledge increased about its functions. TTR is synthesised in a wide range of tissues in humans and other eutherian mammals: the liver, choroid plexus (blood- cerebrospinal ?uid barrier), retinal pigment epithelium of the eye, pancreas, intestine and meninges. However, its sites of synthesis are more restricted in other vertebrates. This implies that the number of tissues synthesising TTR during vertebrate evolution has increased, and raises questions about the selection pressures governing TTR synthesis. TTR is most widely known as a distributor of thyroid hormones. In addition, TTR binds retinol-binding protein, which binds retinol. In this way, TTR is also involved with retinoid distribution. More recently, TTR has been demonstrated to bind a wide variety of endocrine disruptors including drugs, pollutants, industrial compounds, heavy metals, and some naturally occurring plant ?avonoids. These not only interfere with thyroid hormone delivery in the body, but a
出版日期Book 2009
關(guān)鍵詞bacteria; biology; growth; hormone; mutation; neuropeptides; physiology; protein; protein structure; proteins
版次1
doihttps://doi.org/10.1007/978-3-642-00646-3
isbn_softcover978-3-642-42071-9
isbn_ebook978-3-642-00646-3
copyrightSpringer-Verlag Berlin Heidelberg 2009
The information of publication is updating

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d the clinical research into transthyretin.Brings the readerSince its ?rst description in 1942 in both serum and cerebrospinal ?uid, transthyretin (TTR) has had an eventful history, including changes in name from “prealbumin” to “thyroxine-binding prealbumin” to “transthyretin” as knowledge increase
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ey will not be able to act as mechanisms for popular influence at all). Second, their electoral systems function so as to ensure, as nearly as possible, that all votes carry equal weight. Third, they ensure that the impact on government formation of factors other than vote distributions is kept to a
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Vivian Cody,Andrzej Wojtczakis the case for Denmark, Germany and Sweden, donor country strategies remain disappointingly short on strategic thinking. Part of the explanation for this seems to lie in the organizational structure and management systems of the donor agencies themselves.
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Samantha J. Richardsonis the case for Denmark, Germany and Sweden, donor country strategies remain disappointingly short on strategic thinking. Part of the explanation for this seems to lie in the organizational structure and management systems of the donor agencies themselves.
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Porntip Prapunpoj planning concept of ., while in France national reforms recently introduced . as new administrative authorities. This chapter takes into account these particularities, analysing French and German metropolitan policies and thereby exploring complementary or contrasting understandings of metropolitan
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Giuseppe Zanotti,Ileana Ramazzina,Laura Cendron,Claudia Folli,Riccardo Percudani,Rodolfo Bernihood services and and changing environment liabilities. preservation of green belt and countryside, Remedial treatme·nt of contaminated land always prefers new development to be within schemes for requires specialist input, but it is often carried out urban regeneration. for developments designed an
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A. Elisabeth Sauer-Eriksson,Anna Linusson,Erik Lundberg neighbourhood services and and changing environment liabilities. preservation of green belt and countryside, Remedial treatme·nt of contaminated land always prefers new development to be within schemes for requires specialist input, but it is often carried out urban regeneration. for developments designed an978-94-011-1446-2
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