Titlebook: Recent Advances in Thrombosis and Hemostasis; Kenzo Tanaka (Professor Emeritus),Earl W. Davie (P Book 2008 Springer-Verlag Tokyo 2008 Card

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Structure and Biological Function of Factor XI]. Its disorder is inherited as an autosomal recessive trait. Symptoms are variable, mild to severe, and associated with injury or surgery [.]. A half century from the discovery, its purification, amino acid sequence, and crystal structure have been established. Factor XI is the zymogen of a homodim

畸形

Structural Insights into the Life History of Thrombintes and 5 cofactors. How thrombin specificity is directed during the four stages of hemostasis is of great interest to the medical community, as insufficient thrombin activity leads to bleeding and excessive activity results in thrombosis. Over the last three decades we have learned a great deal abo

Inveterate

A Molecular Model of the Human Prothrombinase Complexof calcium ions on a phospholipid membrane surface. The precise details leading to the alteration in catalytic activity of factor Xa have been the center of debate for decades. Our recent crystal structure of activated protein C-inactivated bovine factor Va (factor Va.) revealed a domain organizatio

medium

Lipid Mediators and Tissue Factor Expression response to exogenous and endogenous stimuli, is responsible for the thrombotic complications associated with acute and chronic inflammation. Lipid mediators play key roles in controlling inflammation. Among them, eicosanoids, platelet-activating factor, and lysophospholipids are synthesized in and

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Saline

Biology of an Antithrombotic Factor—ADAMTS13 congenital and acquired defects in ADAMTS13 lead to a potentially fatal syndrome, thrombotic thrombocytopenic purpura (TTP). Here, we describe the structural and functional features of ADAMTS13 and discuss the association between ADAMTS13 deficiency and TTP pathogenesis. ADAMTS13 is mainly synthesi

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Brochure

Coagulation, Inflammation, and Tissue Remodelingxtracellular matrix proteins that often leads to loss of organ function. Recent studies have shown that interaction between the coagulation system and the inflammatory response plays a critical role in wound repair. Soon after tissue injury the coagulation cascade is activated, leading to platelet a