Titlebook: Radionuclide Therapy; Recep Beki?,Berna Polack,Murat Fani Bozkurt Book 2022 The Editor(s) (if applicable) and The Author(s), under exclusi

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Fundamentals of Radiation Safety and Dosimetric Approach in Radionuclide Therapy Applicationsrst used in the local treatment of skin lesions, followed by many new radionuclides [Iodine-131 (I-131), Phosphorus-32 (P-32), Strontium-90 (Sr-90), Samarium-153 (Sm-153)] started to be used in systemic therapy. Recently, several different radiopharmaceuticals such as Gallium-68 (Ga-68) octreotate,

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Radionuclide Therapy in Benign Thyroid Diseases: Nodular Goiter Diseased can be detected in up to 70% of people on ultrasound examination [1]. The majority of thyroid nodules derive from thyroid follicular cells. Benign follicular nodules, the most common mass lesions, can be single or part of a multinodular goiter. Benign thyroid nodules may tend to increase in size o

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Radionuclide Therapy in Neuroendocrine Tumorsive epidemiology study conducted by Yao et al. in 2004 by examining the US Surveillance, Epidemiology and End Results records (SEER database), the NET incidence was found to be 5.25/100,000. However, in this study, the rate of increase in the NET incidence was found to be higher than the rate of inc

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Systemic Treatments and Related Side Effects in Neuroendocrine Tumors, especially gastroenteropancreatic and lung NETs, can be monitored. It may cause local symptoms as well as various clinical conditions based on the hormones it secretes depending on the location [1–3]. Ki-67 index and mitotic index are classified as well-differentiated low grade (grade 1), well-dif

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Radionuclide Therapy in Neuroectodermal Tumorsfor approximately 30 years, is a targeted internal radiotherapy application which is used in the treatment of metastatic, high-risk neuroectodermal tumors. The objective response in the advanced stage and refractory patient group is between 30% and 40% while the symptomatic response is significant.

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Systemic Treatments and Related Side Effects in Neuroectodermal Tumorsmbryonic cells, have common biochemical and genetic characteristics, and are usually seen in childhood and young adults. These tumors are rare especially in adults and can be located in the central nervous system (CNS) or can be seen in many organs [1]. CNS-located PNETs were among the embryological

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Radionuclide Therapy in Liver Tumorson hepatic arterial system in contrast to healthy liver cells that are mostly vascularized from portal venous system. From this point of view, tumor cells can be directly targeted, and healthy liver cells are protected from the possible side effects and complications of high dose radiation to a grea