Titlebook: RNA Towards Medicine; Volker Erdmann,Jan Barciszewski,Jürgen Brosius Book 2006 Springer-Verlag Berlin Heidelberg 2006 DNA.RNAi.Termination

談判

任意

falsehood

Oligonucleotide-Based Antiviral Strategies,tion measures and medical care in poorer countries, greatly facilitates the emergence and dissemination of new virus strains. The appearance of avian influenza viruses that can infect humans, the spread of the severe acute respiratory syndrome (SARS) virus, and the unprecedented raging of human immu

減去

phytochemicals

RNA Aptamers: From Basic Science Towards Therapy,gands (aptamers) from combinatorial oligonucleotide libraries against a target molecule. In the beginning of the technique’s use, RNA molecules were identified that bind to proteins that naturally interact with nucleic acids or to small organic molecules. In the following years, the use of the SELEX

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RNA Aptamers Directed Against Oligosaccharides,rates, abundant constituents of glycoproteins and glycolipids, are not common in cells. Biomedical applications of nucleic acids targeted against oligosaccharides, which are involved in the function of receptors, immune answer, host interaction with invading infectious agents, and cancer metastasis,

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agitate

Application of Aptamers in Therapeutics and for Small-Molecule Detection,ent enzymatic methods. molecule classes. The main focus of this chapter is small molecules as targets. Aptamers are applied complementarily to antibody technologies and can substitute antibodies or small molecules wherever their different properties, such as biochemical nature or highly discriminati

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Ribozymes and siRNAs: From Structure to Preclinical Applications,ent mRNA cleavage. To attain stability, ribozymes and siRNAs must also overcome several other problems, including accessibility to target messenger RNAs (mRNAs), efficient delivery to target cells and unwanted non-specific effects.