Titlebook: RNA Interference and Cancer Therapy; Methods and Protocol Lekha Dinesh Kumar Book 2019 Springer Science+Business Media, LLC, part of Spring

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書目名稱RNA Interference and Cancer Therapy影響因子(影響力)




書目名稱RNA Interference and Cancer Therapy影響因子(影響力)學(xué)科排名




書目名稱RNA Interference and Cancer Therapy網(wǎng)絡(luò)公開度




書目名稱RNA Interference and Cancer Therapy網(wǎng)絡(luò)公開度學(xué)科排名




書目名稱RNA Interference and Cancer Therapy被引頻次




書目名稱RNA Interference and Cancer Therapy被引頻次學(xué)科排名




書目名稱RNA Interference and Cancer Therapy年度引用




書目名稱RNA Interference and Cancer Therapy年度引用學(xué)科排名




書目名稱RNA Interference and Cancer Therapy讀者反饋




書目名稱RNA Interference and Cancer Therapy讀者反饋學(xué)科排名

Antioxidant

siRNA-Based Drug Targeting Human Bcl-xL Against Cancers, to functionally deliver tumor-specific siRNA molecules in nude mice. Here, we introduce an orthotopic tumor inoculation model in nude mice: the resulting orthotopic tumors more closely replicate the clinical conditions in humans—including the metastasis mode—than ectopic subcutaneously inoculated tumors.

deactivate

,Design Strategy to Access siRNA-Encapsulating DNA “Nanosuitcases” That Can Conditionally Release Thstrategies. We present an overview of the design strategy used to access these DNA nanostructures, followed by the steps involved in DNA sequence generation, assembly, and validation of this construct.

褪色

apiary

,Preparation of a?Carrier to Achieve In Vivo Delivery of siRNA: The Example of Chitosan-Coated Poly(e nanoparticles with the siRNA can be achieved by performing an association yield above 90% using a mass ratio of 1 mg siRNA/50 mg of nanoparticles (20?μg siRNA/mg nanoparticles, 1?nmol siRNA (. 14?kDa)/mg nanoparticles).

gerontocracy

dendrites

angiography

Combinatorial siRNA Polyplexes for Receptor Targeting,de a brief background on the formulation design and detailed protocols to evaluate polyplex formation, gene silencing efficiency, and receptor-directed cell killing in cancer cells using targeted combinatorial siRNA polyplexes.

Pigeon

Systemic Modulation of Lymphocyte Subsets Using siRNAs Delivered via Targeted Lipid Nanoparticles,nduce therapeutic gene silencing. This approach utilizes antibodies that decorate lipid nanoparticle surfaces to home into lymphocyte subsets. This approach opens new avenues for discovery of new drug targets and potentially for therapeutics.

Charade

Silencing PRDM14 via Oligonucleotide Therapeutics Suppresses Tumorigenicity and Metastasis of Breasuced the size of tumors and lung metastases in nude mice. In this chapter, we introduce the concept and methods to develop and apply systematically injected small interfering RNA therapy for breast cancer models in vivo.