找回密碼
 To register

QQ登錄

只需一步，快速開始

掃一掃，訪問微社區(qū)

打印 上一主題 下一主題

Titlebook: Quantitative Decisions in Drug Development; Christy Chuang-Stein,Simon Kirby Book 20171st edition Springer International Publishing AG 201

[復制鏈接]
查看: 36615|回復: 51
樓主
發(fā)表于 2025-3-21 19:10:40 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Quantitative Decisions in Drug Development
編輯Christy Chuang-Stein,Simon Kirby
視頻videohttp://file.papertrans.cn/781/780823/780823.mp4
概述Focuses on important decision points and evidence needed for making decisions at these points during the development of a new drug.Takes a holistic approach towards drug development by incorporating k
叢書名稱Springer Series in Pharmaceutical Statistics
圖書封面Titlebook: Quantitative Decisions in Drug Development; Christy Chuang-Stein,Simon Kirby Book 20171st edition Springer International Publishing AG 201
描述.This book offers a high-level treatise of evidence-based decisions in drug development. Because of the inseparable relationship between designs and decisions, a good portion of this book is devoted to the design of clinical trials. The book begins with an overview of product development and regulatory approval pathways. It then discusses how to?incorporate prior knowledge into study design and decision making at different stages of drug development. The latter include selecting appropriate metrics to formulate decisions criteria,?determining go/no-go decisions for progressing a drug candidate to the next stage and?predicting the effectiveness of a product. Lastly, it points out common mistakes made by drug developers under the current drug-development paradigm..The book offers useful insights to statisticians, clinicians, regulatory affairs managers and decision-makers in the pharmaceutical industry who have a basic understanding of the drug-development processand the clinical trials conducted to support drug-marketing authorization.. .The authors provide software codes for select?analytical approaches discussed in the book. The book includes enough technical details to allow stat
出版日期Book 20171st edition
關鍵詞clinical trials; metric for decision; drug development; probability of study success; probability of pro
版次1
doihttps://doi.org/10.1007/978-3-319-46076-5
isbn_softcover978-3-319-83434-4
isbn_ebook978-3-319-46076-5Series ISSN 2366-8695 Series E-ISSN 2366-8709
issn_series 2366-8695
copyrightSpringer International Publishing AG 2017
The information of publication is updating

書目名稱Quantitative Decisions in Drug Development影響因子(影響力)




書目名稱Quantitative Decisions in Drug Development影響因子(影響力)學科排名




書目名稱Quantitative Decisions in Drug Development網(wǎng)絡公開度




書目名稱Quantitative Decisions in Drug Development網(wǎng)絡公開度學科排名




書目名稱Quantitative Decisions in Drug Development被引頻次




書目名稱Quantitative Decisions in Drug Development被引頻次學科排名




書目名稱Quantitative Decisions in Drug Development年度引用




書目名稱Quantitative Decisions in Drug Development年度引用學科排名




書目名稱Quantitative Decisions in Drug Development讀者反饋




書目名稱Quantitative Decisions in Drug Development讀者反饋學科排名




單選投票, 共有 0 人參與投票
 

0票 0%

Perfect with Aesthetics
 

0票 0%

Better Implies Difficulty
 

0票 0%

Good and Satisfactory
 

0票 0%

Adverse Performance
 

0票 0%

Disdainful Garbage
您所在的用戶組沒有投票權(quán)限
沙發(fā)
發(fā)表于 2025-3-22 00:15:26 | 只看該作者
板凳
發(fā)表于 2025-3-22 01:32:12 | 只看該作者
Characteristics of a Diagnostic Test,nt years, companion diagnostics have been developed to preselect patients for specific treatments based on their own biology. In this chapter, we review the metrics commonly used to characterize the performance of a diagnostic test. We then discuss what it means when a diagnostic test returns a posi
地板
發(fā)表于 2025-3-22 07:33:46 | 只看該作者
The Parallel Between Clinical Trials and Diagnostic Tests,on to diagnose is whether the new drug has a clinically meaningful efficacious effect. This comparison offers us the opportunity to apply properties pertaining to diagnostic tests discussed in Chap. 3 to clinical trials. Building on the results in Chap. 3, we discuss why replication is such a critic
5#
發(fā)表于 2025-3-22 12:25:47 | 只看該作者
Incorporating Information from Completed Trials in Future Trial Planning,onsider the Bayesian approach to incorporate existing information into future trial planning. Under the Bayesian approach, prior distributions are used to describe the accumulated knowledge about unknown parameters such as those representing treatment effects. The prior distributions are then used t
6#
發(fā)表于 2025-3-22 13:21:53 | 只看該作者
7#
發(fā)表于 2025-3-22 20:11:51 | 只看該作者
Designing Proof-of-Concept Trials with Desired Characteristics,patients, and if the drug appears to have an effect, whether the size of the effect warrants investment in further development. A number of approaches have been proposed to make a decision for a POC study. In this chapter we review five of them. They are, the traditional hypothesis testing approach,
8#
發(fā)表于 2025-3-23 00:25:14 | 只看該作者
9#
發(fā)表于 2025-3-23 03:19:26 | 只看該作者
10#
發(fā)表于 2025-3-23 05:50:05 | 只看該作者
 關于派博傳思  派博傳思旗下網(wǎng)站  友情鏈接
派博傳思介紹 公司地理位置 論文服務流程 影響因子官網(wǎng) 吾愛論文網(wǎng) 大講堂 北京大學 Oxford Uni. Harvard Uni.
發(fā)展歷史沿革 期刊點評 投稿經(jīng)驗總結(jié) SCIENCEGARD IMPACTFACTOR 派博系數(shù) 清華大學 Yale Uni. Stanford Uni.
QQ|Archiver|手機版|小黑屋| 派博傳思國際 ( 京公網(wǎng)安備110108008328) GMT+8, 2025-10-5 14:13
Copyright © 2001-2015 派博傳思   京公網(wǎng)安備110108008328 版權(quán)所有 All rights reserved
快速回復 返回頂部 返回列表
北海市| 渝北区| 东乡族自治县| 长沙市| 蒲城县| 阆中市| 扬州市| 盐源县| 永清县| 台中市| 门头沟区| 理塘县| 博湖县| 屯留县| 武平县| 金阳县| 淮滨县| 济阳县| 光泽县| 龙泉市| 禹州市| 台山市| 清远市| 日照市| 舟山市| 额尔古纳市| 普宁市| 松阳县| 巴里| 谷城县| 逊克县| 贡觉县| 普兰店市| 靖边县| 安平县| 景德镇市| 岳池县| 永泰县| 浏阳市| 龙泉市| 兰溪市|