| 書目名稱 | Protein-Protein Interaction Networks | | 副標(biāo)題 | Methods and Protocol | | 編輯 | Stefan Canzar,Francisca Rojas Ringeling | | 視頻video | http://file.papertrans.cn/762/761811/761811.mp4 | | 概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts | | 叢書名稱 | Methods in Molecular Biology | | 圖書封面 |  | | 描述 | .This volume explores techniques that study interactions between proteins in different species, and combines them with context-specific data, analysis of omics datasets, and assembles individual interactions into higher-order semantic units, i.e., protein complexes and functional modules. The chapters in this book cover computational methods that solve diverse tasks such as the prediction of functional protein-protein interactions; the alignment-based comparison of interaction networks by .SANA.; using the .RaptorX-ComplexContact. webserver to predict inter-protein residue-residue contacts; the docking of alternative confirmations of proteins participating in binary interactions and the visually-guided selection of a docking model using .COZOID.; the detection of novel functional units by .KeyPathwayMiner. and how .PathClass. can use such de novo pathways to classify breast cancer subtypes. Written in the highly successful .Methods in Molecular Biology.series format, chapters include introductions to their respective topics, lists of the necessary hardware- and software, step-by-step, readily reproducible computational protocols, and tips on troubleshooting and avoiding known pitfa | | 出版日期 | Book 2020 | | 關(guān)鍵詞 | Y2H data; clustering; dynamic networks; protein complexes; topology-based approaches | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4939-9873-9 | | isbn_softcover | 978-1-4939-9875-3 | | isbn_ebook | 978-1-4939-9873-9Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Springer Science+Business Media, LLC, part of Springer Nature 2020 |
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