| 書目名稱 | Protein Pharmacokinetics and Metabolism | | 編輯 | Bobbe L. Ferraiolo,Marjorie A. Mohler,Carol A. Glo | | 視頻video | http://file.papertrans.cn/762/761728/761728.mp4 | | 叢書名稱 | Pharmaceutical Biotechnology | | 圖書封面 |  | | 描述 | Investigation of the pharmacokinetics and metabolism of human proteins has escalated over the last two decades because of the use of recombinant human proteins as therapeutic agents. In addition, the development and improvement of analytical techniques enabling the detection of minute quantities of proteins in biological matrices have aided this process. In assembling this volume, we sought to provide a state-of-the-art as- sessment of the pharmacokinetics and metabolism of protein therapeutics through complete reviews of selected examples. A comprehensive review of all protein therapeutics was not attempted; the majority -of the therapeutic protein classes and crucial scientific issues have been addressed, however. Therefore, we are confident that this volume will provide a useful reference for scientists in this field. The volume has been divided into two general parts. The first part (Chapters 1-3) is composed of general reviews of topics of importance in pharmacokinetic/metabolism studies of proteins: goals and analytical meth- odologies, effects of binding proteins, and effects of antibody induction, respectively. The second part (Chapters 4-8) consists of specific, detailed r | | 出版日期 | Book 1992 | | 關(guān)鍵詞 | biotechnology; cytokine; cytokines; drugs; interferon; kinetics; metabolism; pharmacokinetics; protein; resea | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4899-2329-5 | | isbn_softcover | 978-1-4899-2331-8 | | isbn_ebook | 978-1-4899-2329-5Series ISSN 1078-0467 | | issn_series | 1078-0467 | | copyright | Springer Science+Business Media New York 1992 |
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