| 書目名稱 | Prokaryotic Systems Biology | | 編輯 | Nevan J. Krogan, PhD,Mohan Babu, PhD | | 視頻video | http://file.papertrans.cn/762/761131/761131.mp4 | | 概述 | Provides a foundational knowledge in the understanding of prokaryotic systems biology.Written by leading experts in the field.Enables the microbiology community to create substantive resources to addr | | 叢書名稱 | Advances in Experimental Medicine and Biology | | 圖書封面 |  | | 描述 | .This book focuses on innovative experimental and computational approaches for charting interaction networks in bacterial species. The first part of the volume consists of nine chapters, focusing on biochemical and genetics and genomics approaches including yeast two hybrid, metagenomics, affinity purification in combination with mass spectrometry, chromatin-immunoprecipitation coupled with sequencing, large-scale synthetic genetic screens, and quantitative-based mass spectrometry strategies for mapping the bacterial physical, functional, substrate, and regulatory interaction networks needed for interpreting biological networks, inferring gene function, enzyme discovery, and identifying new drug targets. .The second part comprises five chapters, covering the network of participants for protein folding and complex enzyme maturation. It also covers the structural approaches required to understand bacterial intramembrane proteolysis and the structure and function of bacterial proteins involved in surface polysaccharides, outer membrane, and envelope assembly. .This volume concludes with a focus on computational and comparative genomics approaches, especially network-based methods for | | 出版日期 | Book 2015 | | 關(guān)鍵詞 | genomics; integrative biology; prokaryotes; proteomics; systems biology | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-319-23603-2 | | isbn_softcover | 978-3-319-79508-9 | | isbn_ebook | 978-3-319-23603-2Series ISSN 0065-2598 Series E-ISSN 2214-8019 | | issn_series | 0065-2598 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
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