書目名稱 | Pharmacogenomics | 副標題 | Methods and Protocol | 編輯 | Federico Innocenti | 視頻video | http://file.papertrans.cn/746/745568/745568.mp4 | 概述 | Includes supplementary material: | 叢書名稱 | Methods in Molecular Biology | 圖書封面 |  | 描述 | Expert researchers and physician/clinicians describe in detail the newest and most commonly used technologies today in this rapidly advancing field. The authors provide readily reproducible methods for assessing the functional consequences of a certain polymorphism, evaluate the variety of genotyping platforms currently available, and discuss the management of pharmacogenomic information. Highlights include techniques for making a snapshot of the allele-specific variation in human gene expression, genome wide analysis of allele-specific expression using oligo microarrays, in vivo assays with HaploChIP, SNP genotyping in DNA pools, and PharmGKB, the pharmacogenetics and pharmacogenomics knowledge base. The methodologies for genotyping include denaturing high-performance liquid chromarography, pyrosequencing, kinetic-fluorescence detection, mass spectrometry, and TaqMan assay for insertion/deletions. | 出版日期 | Book 2005 | 關(guān)鍵詞 | Allele; DNA; SNP; gene expression; genes; genetics; genomics; microarray; research | 版次 | 1 | doi | https://doi.org/10.1385/1592599575 | isbn_softcover | 978-1-61737-571-2 | isbn_ebook | 978-1-59259-957-8Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Humana Press 2005 |
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