| 書目名稱 | PET for Drug Development and Evaluation | | 編輯 | D. Comar | | 視頻video | http://file.papertrans.cn/741/740121/740121.mp4 | | 叢書名稱 | Developments in Nuclear Medicine | | 圖書封面 |  | | 描述 | Can drug development and evaluation be improved by the use ofpositron emission tomography (PET)? PET is now well established andmany PET centres participate in networks that warrant the quality oftheir research. PET allows one to follow the effect of a drug on avariety of patients‘ metabolic parameters. In addition, PET may beused to follow the fate in vivo of a compound, allowing visualisationof its binding to specific receptors and a direct study of themechanism of drug action in normal and pathological situations. .The book shows the fields in which PET offers new and uniqueinformation for the development of drugs (conception, toxicity,pharmacokinetics and metabolism, clinical research, and relationsbetween clinical and biological effects) and evaluates fields in whichPET may shorten the development time of drugs. ..Audience:. Professionals in the pharmaceutical industry in allareas of drug discovery and pharmacology, pre-clinical testing,pharmacokinetics and metabolism, clinical evaluation, registration andregulatory affairs. Government health authority representatives whoassess data and documentation on new drug development andradiopharmaceuticals. Academic experts concerned w | | 出版日期 | Book 1995 | | 關(guān)鍵詞 | brain; clinical research; diagnosis; dopamine; drug; drug development; drug discovery; kinetics; metabolism; | | 版次 | 1 | | doi | https://doi.org/10.1007/978-94-011-0429-6 | | isbn_softcover | 978-94-010-4191-1 | | isbn_ebook | 978-94-011-0429-6 | | copyright | Springer Science+Business Media Dordrecht 1995 |
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