Titlebook: Oxidative Stress in Skeletal Muscle; A. Z. Reznick (Senior Lecturer and Researcher),L. Book 1998 Springer Basel AG 1998 Lipid.Oxidation.a

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Oxidative stress and muscle wasting of cachexia,ting accounts for most of the weight loss, which may occur independently of the decreased food intake or malabsorption of nutrients. Moreover, there is evidence to suggest that tumor necrosis factor α (TNFα), may mediate, perhaps in concert with other cytokines, the muscle wasting of cachexia. Howev

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Drug-induced muscle damage,eletal muscle. The extent of skeletal muscle damage can range from that which is minor and self-limiting following drug discontinuation, to muscle weakness which may or may not be ameliorated following drug discontinuation, to rhabdomyolysis which, if not treated, can lead to acute renal failure and

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Drug-induced muscle damage, even death. The mechanisms of drug-induced toxicity are numerous and can range from disruption of intracellular calcium homeostasis, to depletion of cellular energy sources, to free radical mediated mechanisms. This chapter will examine specifically those drugs or substances of abuse which have been shown to cause toxicity to skeletal muscle.

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