| 書目名稱 | Oxidative Stress Mechanisms and their Modulation | | 編輯 | Mohinder Bansal,Naveen Kaushal | | 視頻video | http://file.papertrans.cn/706/705306/705306.mp4 | | 概述 | Gives an overview of mechanisms underlying oxidative stress in lifestyle diseases like diabetes and obesity.Oxidative stress in relation to cancer gives an insight into the disease and its possible ma | | 圖書封面 |  | | 描述 | Research over the years has demonstrated that free radicals mediated oxidative stress lies at the helm of almost all patho-physiological phenomena. These findings emphasize on the need to understand the underlying molecular mechanism(s) and their critical role in the pathogenesis. This book aims to focus on these areas to provide readers a comprehensive outlook about the major redox sensitive pathways and networks involved in various disease conditions. In the first chapter of the book, basic information about the oxidative stress, its generation, its biomarkers and its role in body are discussed. In the next three chapters, the role of oxidative stress in various pathologies ranging from neurological disorders, to cardiovascular diseases, cancers, metabolic diseases and ageing have been described. Chapter 5 cumulatively describes the most important molecular signaling pathways that are affected by reactive oxygen species (ROS). These are the mechanisms which are common denominators invarious pathological states. In the next part of the book, various antioxidant strategies to target and mitigate ROS have been discussed with details on the mechanisms. Selenium, being the research fo | | 出版日期 | Book 2014 | | 關鍵詞 | Antioxidants; Apoptosis; Cell signalling; Gene regulation; ROS | | 版次 | 1 | | doi | https://doi.org/10.1007/978-81-322-2032-9 | | isbn_softcover | 978-81-322-2879-0 | | isbn_ebook | 978-81-322-2032-9 | | copyright | Springer India 2014 |
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