Titlebook: Organelles in Disease; Stine Helene Falsig Pedersen,Diane L. Barber Book 2023 The Editor(s) (if applicable) and The Author(s), under exclu

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Lipid Droplets in Cancer,holipids decorated with various proteins. Often labeled merely as passive fat storage repositories, they in fact have a remarkably dynamic life cycle. Being formed within the endoplasmic reticulum membrane, lipid droplets rapidly grow, shrink, traverse the cytosol, and engage in contacts with other

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Cancer-Related Increases and Decreases in Calcium Signaling at the Endoplasmic Reticulum-Mitochondr of lipid synthesis and represent hubs for ion and metabolite signaling. As these two organelles can module both the amplitude and the spatiotemporal patterns of calcium (Ca.) signals, this particular interaction controls several Ca.-dependent pathways well known for their contribution to tumorigene

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Endosomal Acid-Base Homeostasis in Neurodegenerative Diseases, Overwhelming evidence supports a crucial preclinical role for endosomal dysfunction as an upstream pathogenic hub and driver in Alzheimer’s disease (AD) and related neurodegenerative disorders. We present recent advances on the role of endosomal acid-base homeostasis in neurodegeneration and discus

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Endolysosomal Disorders Affecting the Proximal Tubule of the Kidney: New Mechanistic Insights and T reabsorption of essential nutrients. To function effectively and to achieve homeostasis, these specialized cells require the sorting and recycling of a wide array of cell surface proteins within the endolysosomal network, including signaling receptors, nutrient transporters, ion channels, and polar

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Endo-Lysosomal Cation Channels and Infectious Diseases,laria, tuberculosis, influenza, HIV/AIDS, Ebola, dengue fever, and methicillin-resistant . (MRSA) infection, and most recently Covid-19 (SARS-CoV2). Others with a rather devastating history and high fatality rates such as plague, cholera, or typhus seem less threatening today but have not been eradi

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0303-4240 is book is a valuable resource for physiologists and clinicians alike..Chapter "Lipid Droplets in Cancer" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com..978-3-031-22597-0978-3-031-22595-6Series ISSN 0303-4240 Series E-ISSN 1617-5786