書目名稱 | Optimized Response-Adaptive Clinical Trials |
副標(biāo)題 | Sequential Treatment |
編輯 | Thomas Ondra |
視頻video | http://file.papertrans.cn/704/703338/703338.mp4 |
概述 | Publication in the field of natural sciences.Includes supplementary material: |
叢書名稱 | BestMasters |
圖書封面 |  |
描述 | Two-armed response-adaptive clinical trials are modelled as Markov decision problems to pursue two overriding objectives: Firstly, to identify the superior treatment at the end of the trial and, secondly, to keep the number of patients receiving the inferior treatment small. Such clinical trial designs are very important, especially for rare diseases. Thomas Ondra presents the main solution techniques for Markov decision problems and provides a detailed description how to obtain optimal allocation sequences. |
出版日期 | Book 2015 |
關(guān)鍵詞 | Allocation Sequence; Backward Induction; Clinical Trial Designs; Policy Iteration; Value Iteration |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-658-08344-1 |
isbn_softcover | 978-3-658-08343-4 |
isbn_ebook | 978-3-658-08344-1Series ISSN 2625-3577 Series E-ISSN 2625-3615 |
issn_series | 2625-3577 |
copyright | Springer Fachmedien Wiesbaden 2015 |