Titlebook: Optical Imaging of Brain Function and Metabolism; Ulrich Dirnagl,Arno Villringer,Karl M. Einh?upl Book 1993 The Editor(s) (if applicable)

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Measurement of Human Hypothermic Cerebral Oxygen Metabolism by Transmission Spectroscopy the cerebrovascular compartment have unique infrared absorption spectra which influence wavelength specific attenuation in this wavelength band (Tamura et al. 1985). The human brain contains 600 to 1000 mg of hemoglobin per 100 grams of tissue; thus, the brain is an excellent organ for . optical sp

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Optical CT Imaging of Hemoglobin Oxygen-Saturation Using Dual-Wavelength Time Gate Techniquetion spectroscopy (Jobsis, 1977, Chance et al. 1988, Delpy et al. 1988). This is based on the fact that oxyhemoglobin and deoxyhemoglobin have different absorption spectra in the near infrared region, where light absorption by other tissues is relatively weak. However, although tissues are quite tra

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Optical Imaging of the Functional Architecture in Cat Visual Cortex: The Layout of Direction and Ori 1957; Hubel and Wiesel, 1965): neurons lying below each other from the pia to the white matter - despite some lamina-dependent differences - share important functional properties. A method which has proven to be very useful for investigating the functional architecture across a cortical area is the

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Mapping of Neural Activity Patterns Using Intrinsic Optical Signals: From Isolated Brain Preparation(reviewed in Cohen, 1973). There are several possible cellular mechanisms which could underlie activity-dependent changes in the optical properties of neuronal tissue. These include neuronal and glial swelling (MacVicar and Hochman, 1991), neurosecretion (Salzberg ., 1985) and the rapid reorientatio

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Fiber Optic Imaging of Subcortical Neural Tissue in Freely Behaving Animals However, electrophysiological techniques are limited in the number of individual cells that can be recorded simultaneously. Correlates of neural activity are also measured in two or three dimensional space with procedures such as Positron Emission Tomography or Magnetic Resonance Imaging. However,

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