Titlebook: Obesity: Pathology and Therapy; Dean H. Lockwood (Vice President),Thomas C. Heffne Book 2000 Springer-Verlag Berlin Heidelberg 2000 CNS.Fe

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Health Implications of Obesitysk have been shown to increase with increasing weight in population studies. In addition, it has become evident that central fat distribution has a negative impact on health. This chapter describes the epidemiologic evidence that defines the risks of obesity and of fat distribution on morbidity and mortality.

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Popular Diets and Other Treatments of Obesity, or BMI greater than 27.8 for males and 27.2 for females has adverse affects on health and longevity and diet (NATIONAL INSTITUTES OF HEALTH CONSENSUS DEVELOPMENT CONFERENCE STATEMENT HEALTH IMPLICATIONS OF OBESITY).

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The Surgical Treatment of Morbid Obesityhese, at least 12 million are morbidly obese, exceeding their ideal body weight by more than 100 pounds (KUCZMARSKI et al. 1994; NATIONAL TASK FORCE ON PREVENTION AND TREATMENT OF OBESITY 1994). In minority populations, obesity rates are out of proportion; nearly 50% of African American, Mexican American, and Native American women are overweight.

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The Influence of Obesity on the Development of Non-Insulin-Dependent Diabetes Mellitusplete reversal of the diabetic state. This review will summarize some of the mechanisms involved in the development of type 2 diabetes in obese and overweight individuals. A broad scheme highlighting the pathophysiology of this process is shown in Fig. 1.

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The Regulation of Body Weight: Set-Points and Obesitycontrol processes exist for the purpose of maintaining a stable internal environment, provided an empirically testable model, which formed the basis for the scientific investigation of regulatory physiology in the twentieth century.

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Serotonin Drugs and the Treatment of Obesity neurotoxic lessioning of 5-HT neurons (with 5,7-dihyroxytrytamine, 5,7-DHT), or preventing 5-HT synthesis (using para-chlorophenylanine, pCPA) which depletes neuronal 5-HT, not only prevented 5-HT induced hypophagia but increased food intake (MACKENZIE et al. 1979).

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0171-2004 ng factor in a variety of diseases, there is now widespread agreement that obesity itself should be classified and treated as a disease and that it has important conse- quences for personal health, quality of life and cost to society. Understanding obesity and the means of treating it have been hamp