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Titlebook: Neurophysiologic Biomarkers in Neuropsychiatric Disorders; Etiologic and Treatm Daniel C. Javitt,James C. McPartland Book 2024 The Editor(s

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書(shū)目名稱Neurophysiologic Biomarkers in Neuropsychiatric Disorders
副標(biāo)題Etiologic and Treatm
編輯Daniel C. Javitt,James C. McPartland
視頻videohttp://file.papertrans.cn/670/669653/669653.mp4
概述Offers a comparative review of biomarkers across major mental health disorders.Discusses applications to drug development via the 21st Century Cares Act.Presents a translational approach to appeal to
叢書(shū)名稱Advances in Neurobiology
圖書(shū)封面Titlebook: Neurophysiologic Biomarkers in Neuropsychiatric Disorders; Etiologic and Treatm Daniel C. Javitt,James C. McPartland Book 2024 The Editor(s
描述.This book reviews neurophysiological biomarkers in neuropsychiatric disorders from the viewpoint of the 21st Century Cures Act, which encourages the use of biomarkers for a variety of purposes during drug development. It covers both traditional etiologic uses of biomarkers and the more recent Biomarkers, EndpointS, and other Tools (BEST) classification scheme used by the FDA, which permits biomarkers for purposes of susceptibility, diagnosis, monitoring, prognosis, pharmacodynamics/response, and safety. The first section of the book describes potential uses of neurophysiologic biomarkers. Subsequent sections focus on a wide range of conditions, including schizophrenia, autism spectrum disorder, Parkinson’s disease, and depression, as well as cross-diagnostic and translational uses, including monkey and rodent analogs. The purpose of the book is to help clinicians understand how neurophysiological biomarkers may be used to understand and manage clinical conditions; to help researchers to understand how biomarkers may be used translationally to test specific theories; and to help pharma investigators to understand how biomarkers can be used to accelerate treatment development..
出版日期Book 2024
關(guān)鍵詞schizophrenia; psychiatry; autism; cognition; fMRI; event-related potentials; cerebral blood volume; dement
版次1
doihttps://doi.org/10.1007/978-3-031-69491-2
isbn_softcover978-3-031-69493-6
isbn_ebook978-3-031-69491-2Series ISSN 2190-5215 Series E-ISSN 2190-5223
issn_series 2190-5215
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

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Book 2024use of biomarkers for a variety of purposes during drug development. It covers both traditional etiologic uses of biomarkers and the more recent Biomarkers, EndpointS, and other Tools (BEST) classification scheme used by the FDA, which permits biomarkers for purposes of susceptibility, diagnosis, mo
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Biomarker Methodologies: A NIMH Perspectiveel interventions. This chapter highlights examples of biomarker technologies that have been utilized to advance understanding of the pathophysiology of psychiatric disorders and the development of novel therapeutics.
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Rodent Models for ASD Biomarker Developmented by current knowledge of genetics, molecular biology, and bioinformatics. These ASD-associated rodent models enable quantifiable biomarker development. Finally, we discuss the prospects of ASD biomarker development.
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發(fā)表于 2025-3-23 00:57:45 | 只看該作者
The Use of Event-Related Potentials in the Study of Schizophrenia: An Overview leading hypotheses about the pathophysiology of schizophrenia. We conclude with an evaluation of both the utility and limitations of ERPs in schizophrenia research and offer recommendations of future directions that may be beneficial to the field.
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發(fā)表于 2025-3-23 03:58:36 | 只看該作者
Gamma Oscillations as a Biomarker of Neural Circuit Function in Psychosis: Where Are We, and Where Devidence for this hypothesis is critically reviewed, focusing on studies in the areas of visual feature binding, auditory steady-state response, and spontaneous gamma activity. The current state of the field is discussed, and recommendations for future directions are presented.
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