Titlebook: Nucleic Acid Therapeutics in Cancer; Alan M. Gewirtz Book 2004 Springer Science+Business Media New York 2004 DNA.cancer.tumor.tumor growth

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Mechanism of Action of Antisense RNA in Eukaryotic Cellsal years that the formation of double-stranded RNA (dsRNA), triggers a variety of cellular effects that depend not only on the length of the RNA duplex, but also on its intracellular location and on the cell type .. These effects include activation of the protein kinase (PKR) and RNase L pathways, i

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Considerations on the Design of Antisense OligonucleotidessON. This annealing step seems to be strongly influenced by the complex target structure and by characteristics of the asON sequence itself. It is desirable to understand those characteristics because the selection of favorable local target motifs along along-chain target RNA crucially determines ef

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Eric Vivès PhD,Jean Philippe Richard MSc,Bernard Lebleu PhDvol 539 1983: vol 1117 1993: vol 1608 2000: vol 1816 1976: vol 598 1984: vol 1180 1994: vol 1648 2001: vol 1837 & 1851 1977: vol 678 1985/86/87: vol 1362 & S-50 2002: vol 1840 1978: vol 774 198978-3-540-30988-8978-3-540-34806-1Series ISSN 0075-8434 Series E-ISSN 1617-9692

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Lida K. Gifford PhD,Ponzy Lu PhD,Alan M. Gewirtz MDvol 539 1983: vol 1117 1993: vol 1608 2000: vol 1816 1976: vol 598 1984: vol 1180 1994: vol 1648 2001: vol 1837 & 1851 1977: vol 678 1985/86/87: vol 1362 & S-50 2002: vol 1840 1978: vol 774 198978-3-540-30988-8978-3-540-34806-1Series ISSN 0075-8434 Series E-ISSN 1617-9692

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Joanna B. Opalinska MD,Susan E. Shetzline PhDvol 539 1983: vol 1117 1993: vol 1608 2000: vol 1816 1976: vol 598 1984: vol 1180 1994: vol 1648 2001: vol 1837 & 1851 1977: vol 678 1985/86/87: vol 1362 & S-50 2002: vol 1840 1978: vol 774 198978-3-540-30988-8978-3-540-34806-1Series ISSN 0075-8434 Series E-ISSN 1617-9692

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Rosel Kretschmer-Kazemi Far PhD,Jens M. Warnecke PhD,Georg Sczakiel PhD81: vol 976 1991: vol 1541 1998: vol 1738 1974: vol 480 1982: vol 1097 1992: vol 1581 1999: vol 1781 1975: vol 539 1983: vol 1117 1993: vol 1608 2000: vol 1816 1976: vol 598 1984: vol 1180 1994: vol 1648 2001: vol 1837 & 1851 1977: vol 678 1985/86/87: vol 1362 & S-50 2002: vol 1840 1978: vol 774 198

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