找回密碼
 To register

QQ登錄

只需一步,快速開始

掃一掃,訪問微社區(qū)

打印 上一主題 下一主題

Titlebook: Nuclear Receptors; The Art and Science Mostafa Z. Badr Book 2021 The Editor(s) (if applicable) and The Author(s), under exclusive license

[復(fù)制鏈接]
查看: 21717|回復(fù): 60
樓主
發(fā)表于 2025-3-21 18:22:49 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Nuclear Receptors
副標(biāo)題The Art and Science
編輯Mostafa Z. Badr
視頻videohttp://file.papertrans.cn/669/668679/668679.mp4
概述Covers how produced modulators are evaluated experimentally and eventually in relevant disease states, before reaching the phase of developing more efficient and/or less toxic therapies.Explains how s
圖書封面Titlebook: Nuclear Receptors; The Art and Science  Mostafa Z. Badr Book 2021 The Editor(s) (if applicable) and The Author(s), under exclusive license
描述Nuclear receptors are ligand activated transcription factors that control numerous biological functions. Consequently, altering activity of these receptors is proposed, and indeed documented, to affect many physiological and pathological conditions in experimental animals and humans. Thus, nuclear receptors have become a major target in the effort to treat numerous diseases..This book will shed light on and emphasize intricate processes involved in designing as well as discovering physiological and pharmacological modulators of these important proteins.?World-renowned scientists will share with the reader their professional expertise and extensive experience acquired through decades working with nuclear receptors. Chapters address?the various means and consequences of modulating nuclear receptor activity will be presented and discussed.?These modulators cover a wide span of moieties ranging from synthetic chemicals to natural products. In addition, the classification of these chemicals ranges from pan agonists to selective agonists and inverse agonists to antagonists. They also include proteolytic means to obliterate the receptor in the event that modulating its activity through ca
出版日期Book 2021
關(guān)鍵詞molecular pharmacology; drug design; PPAR; PXR; metabolic diseases; vitamin d receptor; ligand; target tran
版次1
doihttps://doi.org/10.1007/978-3-030-78315-0
isbn_softcover978-3-030-78438-6
isbn_ebook978-3-030-78315-0
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

書目名稱Nuclear Receptors影響因子(影響力)




書目名稱Nuclear Receptors影響因子(影響力)學(xué)科排名




書目名稱Nuclear Receptors網(wǎng)絡(luò)公開度




書目名稱Nuclear Receptors網(wǎng)絡(luò)公開度學(xué)科排名




書目名稱Nuclear Receptors被引頻次




書目名稱Nuclear Receptors被引頻次學(xué)科排名




書目名稱Nuclear Receptors年度引用




書目名稱Nuclear Receptors年度引用學(xué)科排名




書目名稱Nuclear Receptors讀者反饋




書目名稱Nuclear Receptors讀者反饋學(xué)科排名




單選投票, 共有 0 人參與投票
 

0票 0%

Perfect with Aesthetics

 

0票 0%

Better Implies Difficulty

 

0票 0%

Good and Satisfactory

 

0票 0%

Adverse Performance

 

0票 0%

Disdainful Garbage

您所在的用戶組沒有投票權(quán)限
沙發(fā)
發(fā)表于 2025-3-21 22:57:37 | 只看該作者
板凳
發(fā)表于 2025-3-22 03:31:21 | 只看該作者
Multifaceted Effects of Ligand on Nuclear Receptor Mobility,partments and in their intranuclear dynamics. This chapter highlights key features of three main categories of intracellular localization into which the nuclear receptors can be roughly sorted: ligand-dependent nuclear accumulation, ligand-dependent intranuclear localization, and ligand-independent trafficking.
地板
發(fā)表于 2025-3-22 08:38:27 | 只看該作者
Pregnane X Receptor: Understanding Its Function and Activity at the Molecular Level,tain diseases, such as inflammatory bowel disease. This book chapter describes the molecular basis of PXR activity, correlating biochemical and structural elements to describe the promiscuous nature of PXR in recognizing a wide array of chemicals and the challenges in developing PXR modulators.
5#
發(fā)表于 2025-3-22 09:49:39 | 只看該作者
6#
發(fā)表于 2025-3-22 16:44:29 | 只看該作者
,PPARα and δ Ligand Design: Honing the Traditional Empirical Method with a More Holistic Overview,ntify common ligand design factors for selectivity towards a PPAR subtype. Methods to improve drug-lead identification and optimization and other factors that may contribute to design of a successful PPAR ligand are discussed.
7#
發(fā)表于 2025-3-22 18:54:21 | 只看該作者
8#
發(fā)表于 2025-3-23 00:17:23 | 只看該作者
Use of Nanotechnology to Improve 15d-PGJ2 Immunomodulatory Activities,we focus on how 15d-PGJ. is involved in the resolution of inflammatory responses and as potential analgesic molecule. Importantly, we will present evidences that nanotechnology (nanocarriers) is a helpful tool to improve its action and bioavailability.
9#
發(fā)表于 2025-3-23 04:58:12 | 只看該作者
ng more efficient and/or less toxic therapies.Explains how sNuclear receptors are ligand activated transcription factors that control numerous biological functions. Consequently, altering activity of these receptors is proposed, and indeed documented, to affect many physiological and pathological co
10#
發(fā)表于 2025-3-23 06:05:09 | 只看該作者
978-3-030-78438-6The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
 關(guān)于派博傳思  派博傳思旗下網(wǎng)站  友情鏈接
派博傳思介紹 公司地理位置 論文服務(wù)流程 影響因子官網(wǎng) 吾愛論文網(wǎng) 大講堂 北京大學(xué) Oxford Uni. Harvard Uni.
發(fā)展歷史沿革 期刊點(diǎn)評 投稿經(jīng)驗(yàn)總結(jié) SCIENCEGARD IMPACTFACTOR 派博系數(shù) 清華大學(xué) Yale Uni. Stanford Uni.
QQ|Archiver|手機(jī)版|小黑屋| 派博傳思國際 ( 京公網(wǎng)安備110108008328) GMT+8, 2025-10-6 05:03
Copyright © 2001-2015 派博傳思   京公網(wǎng)安備110108008328 版權(quán)所有 All rights reserved
快速回復(fù) 返回頂部 返回列表
永昌县| 高邮市| 青川县| 崇明县| 仁布县| 那坡县| 乌兰察布市| 板桥市| 慈利县| 平昌县| 博客| 民丰县| 米脂县| 固安县| 手游| 玉门市| 盐源县| 陆川县| 增城市| 上犹县| 崇明县| 陕西省| 洛宁县| 云林县| 马尔康县| 通榆县| 扎囊县| 马鞍山市| 杨浦区| 和林格尔县| 西藏| 武城县| 保亭| 古田县| 米泉市| 安吉县| 长垣县| 科尔| 敦煌市| 万源市| 辽阳市|