Titlebook: Novel Immune Potentiators and Delivery Technologies for Next Generation Vaccines; Manmohan Singh Book 2013 Springer Science+Business Media

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Preclinical and Clinical Development of Synthetic ,NKT-Cell Glycolipid Agonists as Vaccine Adjuvantsss a semi-invariant T-cell receptor (TCR), Vα14-Jα18 paired with Vβ8.2, Vβ7 or Vβ2 in mice and Vα24-Jα18/Vβ11 in human [1–5]. These cells are referred to as .NKT cells type I NKT cells, or NKT cells, in contrast to type II NKT cells comprising the remaining NKT cells expressing non-invariant TCR [6]

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Mucosal Vaccination: Opportunities and Challengeson. Mucosal surfaces, with a combined surface area of about 400 m. [1], are undoubtedly the major site of entry for most pathogens. Therefore, these vulnerable surfaces are associated with a large and highly specialized innate and adaptive mucosal immune system that protects the surfaces and the bod

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High Throughput Screening for Stabilizers of Vaccine Antigensed, its conversion into an efficacious, safe, convenient, and stable dosage form that can be effectively delivered to a target population is often beset with numerous difficulties. Not the least of these is the many different types of vaccine antigens, each with its own individual chemical identity,

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Current Status of Electroporation Technologies for Vaccine Deliveryby the plasmid and controlled by mammalian promoters, the stage was set for the investigation of the range of compelling applications for endogenous expression of proteins in animals and humans [1]. The finding that simple injection of purified plasmid DNA into a target tissue could induce sustained

Excitotoxin

Microneedles for Intradermal Vaccination: Immunopotentiation and Formulation Aspects. Ease of administration, improved immune protection, antigen dose sparing, and independence of cold-chain distribution are among the many potential benefits that the technology can introduce in the field [2]. Due to the same advantages, microneedle-based vaccines, and intradermal vaccination in gen

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