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Titlebook: Notch Signaling in Embryology and Cancer; Molecular Biology of J?rg Reichrath,Sandra Reichrath Book 2020Latest edition The Editor(s) (if ap

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書目名稱Notch Signaling in Embryology and Cancer
副標題Molecular Biology of
編輯J?rg Reichrath,Sandra Reichrath
視頻videohttp://file.papertrans.cn/669/668234/668234.mp4
概述The content is presented in a logical and coherent structure, enabling the reader to readily access relevant information.The volume editors are renowned experts on Notch and Notch Signaling and the ch
叢書名稱Advances in Experimental Medicine and Biology
圖書封面Titlebook: Notch Signaling in Embryology and Cancer; Molecular Biology of J?rg Reichrath,Sandra Reichrath Book 2020Latest edition The Editor(s) (if ap
描述.This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It summarizes the newest achievements on this topic from Notch’s flag-ship function in the development of the embryo and for various inherited diseases to the Notch signaling pathway’s role in the development of leukemia and in a number of cancers, including skin cancer, intestinal cancer and others. Additionally, the emerging new role of the Notch signaling pathway as a promising target for prevention and therapy of various diseases, including cancer, is discussed. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role for embryologic tissue patterning, for stem cells, in senescence, and on the regulation of Notch signaling by epigenetic and other factors including microRNAs, long non-codingRNAs, and more.?.Taken as a whole, with its companion books – .Notch Signaling in Embryology. and .Notch Signaling in Cancer. – this is a definitive discussion of the
出版日期Book 2020Latest edition
關鍵詞Notch; Notch Signaling; Embryology; Microbiome and Cancer; Notch and senescence; Regulation of Notch Sign
版次2
doihttps://doi.org/10.1007/978-3-030-36422-9
isbn_softcover978-3-030-36424-3
isbn_ebook978-3-030-36422-9Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

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Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/n/image/668234.jpg
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A Snapshot of the Molecular Biology of Notch Signaling: Challenges and Promises,at regulate key cell fate decisions and other core processes. This chapter gives a short introduction to the first volume of the book entitled ., that is intended to provide both basic scientists and clinicians who seek today`s clearest understanding of the molecular mechanisms that mediate Notch si
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Ligand-Induced Cis-Inhibition of Notch Signaling: The Role of an Extracellular Region of Serrate,ing the Notch receptor on one cell can be activated in trans by ligands on an adjacent cell leading to alteration of transcription and cellular fate. Ligands also have the ability to inhibit Notch signaling, and this can be accomplished when both receptor and ligands are coexpressed in cis on the sa
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Maheshvara, a Conserved RNA Helicase, Regulates Notch Signaling in , with co- and post-transcriptional regulation. These processes are controlled via the involvement of a multitude of RNA binding proteins (RBPs). Innumerable human diseases have been associated with altered expression of RNA binding proteins. In this chapter we have focused on . (.) which encodes a p
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