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Titlebook: Non-Protein Coding RNAs; Nils G. Walter (Associate Professor of Chemistry), Book 2009 Springer-Verlag Berlin Heidelberg 2009 Einzelmolekül

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發(fā)表于 2025-3-21 16:27:56 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Non-Protein Coding RNAs
編輯Nils G. Walter (Associate Professor of Chemistry),
視頻videohttp://file.papertrans.cn/668/667010/667010.mp4
概述Biophysical perspective on a rapidly expanding number of non-protein coding RNAs.Overview on how non-protein coding RNAs work and how biophysical techniques and other probing techniques help delineate
叢書名稱Springer Series in Biophysics
圖書封面Titlebook: Non-Protein Coding RNAs;  Nils G. Walter (Associate Professor of Chemistry), Book 2009 Springer-Verlag Berlin Heidelberg 2009 Einzelmolekül
描述The 2006 Nobel Prize in Physiology or Medicine was awarded to the discoverers of RNA interference, Andrew Fire and Craig Mello. This prize, which follows “RNA” Nobels for splicing and RNA catalysis, highlights just one class of recently discovered non-protein coding RNAs. Remarkably, non-coding RNAs are thought to outnumber protein coding genes in mammals by perhaps as much as four-fold. In fact, it appears that the complexity of an organism correlates with the fraction of its genome devoted to non-protein coding RNAs. Essential biological processes as diverse as cell differentiation, suppression of infecting viruses and parasitic tra- posons, higher-level organization of eukaryotic chromosomes, and gene expression are found to be largely directed by non-protein coding RNAs. Currently, bioinformatic, high-throughput sequencing, and biochemical approaches are identifying an increasing number of these RNAs. Unfortunately, our ability to characterize the molecular details of these RNAs is significantly lacking. The biophysical study of these RNAs is an emergent field that is unraveling the molecular underpinnings of how RNA fulfills its multitude of roles in sustaining cellular life.
出版日期Book 2009
關鍵詞Einzelmolekülmikroskopie; FRET; Kernspinresonanz; Nuclear Magnetic Resonance; Riboswitch RNA; R?ntgenstru
版次1
doihttps://doi.org/10.1007/978-3-540-70840-7
isbn_softcover978-3-642-08980-0
isbn_ebook978-3-540-70840-7Series ISSN 0932-2353 Series E-ISSN 1868-2561
issn_series 0932-2353
copyrightSpringer-Verlag Berlin Heidelberg 2009
The information of publication is updating

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The Small Ribozymes: Common and Diverse Features Observed Through the FRET Lens,xtensively used to detect conformational changes in these ribozymes and dissect their reaction pathways. Common and diverse features are beginning to emerge that, by extension, highlight general biophysical properties of non-protein coding RNAs.
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地板
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Group I Ribozymes as a Paradigm for RNA Folding and Evolution,dies on group I splicing factors demonstrate how proteins facilitate the assembly of splicing complexes by stabilizing tertiary interactions between domains and by ATP-dependent cycles of RNA unfolding.
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Forms and Functions of Telomerase RNA,and spliceosome that evolved from catalytic RNAs of the RNA World. However, unlike these RNPs, telomerase evolved its RNP identity after advent of the Protein World. Insights about telomer-ase have broad significance for understanding non-coding RNA biology as well as chromosome end maintenance and human disease.
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