Titlebook: Non-Hodgkin‘s Lymphoma in Childhood and Adolescence; Oussama Abla,Andishe Attarbaschi Book 2019 Springer Nature Switzerland AG 2019 B-lymp

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Epidemiology of Non-Hodgkin Lymphomas in Childhood and Adolescencea (NHL) encompasses a diverse group of lymphoid neoplasms cumulatively accounting for 7% of all malignancies under the age of 19?years. Childhood NHLs are distinct from the adult counterpart and are mainly high-grade neoplasms. Across all histology and age groups males have a higher incidence of NHL

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Pathogenesis of B-Cell Lymphomae genetic changes are at least in part introduced through somatic mutation machineries which B-cells need to fulfill their physiologic tasks in adaptive immunity. The transformed malignant B-cells are frozen at distinct maturation stages, a feature which aids to their classification based on morphol

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