Titlebook: Nitric Oxide (NO) and Cancer; Prognosis, Preventio Benjamin Bonavida Book 2010 Springer Science+Business Media, LLC 2010 apoptosis.cancer.c

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Nitric Oxide and Cancer: An Overviewinogenesis, tumor progression, genotoxicity, and angiogenesis. Previously, it has been demonstrated that NO may perform different functions dependent on NO levels achieved in a particular microenvironment. Furthermore, researchers also have discovered and identified the various sources of NO, which

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Nitric Oxide Expression in Cancerthe distribution of the different NOS isoforms is largely related to their respective functions. Vascular endothelial NOS (eNOS) is important for cardiovascular homeostasis, vessel remodeling and angiogenesis; neuronal NOS (nNOS) is expressed in neurons, primarly in the cerebellum and hippocampus an

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Cytotoxic and Protective Activity of Nitric Oxide in Cancersry roles in many biological events under physiological and pathological conditions. NO promotes apoptosis in some tumor cells, but provokes anti-apoptotic activity in other tumor cells. For this reason, conflicting viewpoints have arisen as to whether nitric oxide is cytotoxic or protective in cance

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Cytotoxic/Protective Activity of Nitric Oxide in Cancerences have reported two facets of NO as a possible mediator of cancer development and anti-cancer therapeutics. The paradoxical action of NO in cancer biology depends on concentration, chemical variability, cancer microenvironment, etc. As an anti-cancer therapeutic, NO may be useful as in vivo chem

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crease

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