Titlebook: Nicotinic Acetylcholine Receptor Technologies; Ming D. Li Book 2016 Springer Science+Business Media New York 2016 nAChR subunits.nicotinic

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憤慨點(diǎn)吧

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衰弱的心

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https://doi.org/10.1007/978-1-4939-3768-4nAChR subunits; nicotinic drugs; chronoamperometry; nucleotide polymorphism; nicotinic ligands

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overture

Zebrafish: An Animal Model to Study Nicotinic Drugs on Spatial Memory and Visual Attention, memory of the spatial location of reward. Visual attention is studied using a virtual object recognition test (VORT) where two geometrical 2D virtual shapes are presented stationary on two iPod screens. Shape recognition is scored in terms of exploration time whenever the zebrafish approach to the

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Conditioned Place Preference and Behavioral Analysis to Evaluate Nicotine Reinforcement Properties ol group, which did not show a significant place preference shift, providing evidence that the preference shift in the nicotine-paired group was not due to a reduction of aversion for the initially aversive compartment. Nicotine-induced place preference in zebrafish was corroborated by behavioral an

乳白光

Emerging Technologies in the Analysis of , Nicotinic Acetylcholine Receptors,for identifying and characterizing genes involved in their biological regulation in the nervous system. These methods can be easily adapted to the study of other organisms as well as other receptor classes.

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Using Natural Genetic Variability in Nicotinic Receptor Genes to Understand the Function of Nicotinehavioral and physiological responses to nicotine, a knockin mouse was generated. Studies with this knockin mouse as outlined in this chapter indicated the . T529A polymorphism was sufficient to affect both nAChR function and nicotine induced behaviors.