Titlebook: New Trends in Pharmacokinetics; Aldo Rescigno,Ajit K. Thakur Book 1991 Plenum Press, New York 1991 drug.drug development.kinetics.metaboli

Firefly

Imaging Techniques in Pharmacology,s of soil, or toxins. These drugs are “designed”, rather than “discovered.” Following identification of a likely compound in-vitro, careful studies are performed in animal models to determine the pharmacokinetics and pharmacodynamics of the drug. Once identified as safe and efficacious in animal tri

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Pitfalls in Pharmacokinetic Modeling of Monoclonal Antibody Biodistribution in Man,reasingly accepted as a routine diagnostic procedure, particularly for staging patients with cancer. In fact, even though the diagnostic potentials of immunoscintigraphy have been explored for diverse applications including cardiovascular diseases (for the detection of thrombi or of damaged myocardi

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Interspecies Scaling in Pharmacokinetics,pharmacokinetics” signifies the prediction of . chemical disposition behavior in untested species from the experimental observations made in one or more species. Interspecies scaling of the pharmacokinetic processes (i.e., uptake, distribution and clearance) of chemicals can be performed by (1) allo

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Implications of Stereoselectivity in Clinical Pharmacokinetics,e stereochemical pure due to the stereospecificity of biological synthesis. By contrast, most of the drugs with a chiral center produced by chemical synthesis are only available as racemates, since chemical synthesis usually leads to a racemate unless stereospecific synthesis is employed [Roth & Kle

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