Titlebook: New Targets in Inflammation; Inhibitors of COX-2 Nicolas Bazan,Jack Botting,John Vane Conference proceedings 1996 Springer Science+Busines

HARDY

書目名稱New Targets in Inflammation影響因子(影響力)




書目名稱New Targets in Inflammation影響因子(影響力)學(xué)科排名




書目名稱New Targets in Inflammation網(wǎng)絡(luò)公開度




書目名稱New Targets in Inflammation網(wǎng)絡(luò)公開度學(xué)科排名




書目名稱New Targets in Inflammation被引頻次




書目名稱New Targets in Inflammation被引頻次學(xué)科排名




書目名稱New Targets in Inflammation年度引用




書目名稱New Targets in Inflammation年度引用學(xué)科排名




書目名稱New Targets in Inflammation讀者反饋




書目名稱New Targets in Inflammation讀者反饋學(xué)科排名

陳腐的人

stress-response

erythema

Adhesion molecules as targets for therapy in rheumatoid arthritis,enules and mononuclear cells in the circulation, mediated by a variety of adhesion molecules, govern the entry of inflammatory cells into the tissues.. Interference with these interactions, therefore, might be effective in the therapy of RA.

Trabeculoplasty

Platelet

atory group. In 1971 Vane pro- posed that both the beneficial and toxic actions of these drugs was through inhibition of prostaglandin synthesis. The recent discovery that prostaglandins responsible for pain and other symptoms at inflammatory foci are synthesized by an inducible cyclooxygenase (COX-

帶子

Cyclooxygenase-2 and intestinal cancer,exhibit chemoprotective effects as judged by a reduction in the frequency and number of premalignant and malignant lesions. Recently, Jacoby et al.. reported a decrease in tumour number in Min (multiple intestinal neoplasia) mice treated with piroxicam.

等級的上升

granite

Structure of prostaglandin H2 synthase-1 (COX-1) and its NSAID binding sites,c acid to form the intermediate PGG., and a peroxidase activity which reduces the hydroperoxide moiety of PGG. to the corresponding alcohol and produces PGH... This PGН. is acted upon by other enzymes to produce the final hormone product, which is secreted from the cell.

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