Titlebook: New Drugs, Concepts and Results in Cancer Chemotherapy; F. M. Muggia Book 1991 Springer Science+Business Media New York 1991 cancer.chemot

Objective

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Licentious

encomiast

Pharmacology and clinical investigation of SR-2508 (etanidazole)he abnormal metabolic environment of solid tumors. It is proposed that the disordered vascular development in the growing tumor mass results in a proportion of cells being remote from capillaries; the increased diffusion distance leads to hypoxia, low glucose concentrations, and reduced cellular pH

凝視

Folate antimetabolites inhibitory to , purine synthesisalogs that were more active than methotrexate or, at least, that had different properties than this important folate antimetabolite. After 40 years of preclinical and clinical investigation, methotrexate is still in clinical use and still represents the only folate analog in widespread therapeutic a

enumaerate

Taxol: A new agent active in melanoma and ovarian cancercharacterized by Wani et al. [l]. This drug is a complex ester,consisting of a taxane derivative with an oxetan ring, an unusual chemical structure (as shown in figure 1) whose biological activity had not been previously studied.

plasma-cells

ICRF-187 (ADR-529) cardioprotection against anthracycline-induced cardiotoxicity: Clinical and preclronic dose-dependent cardiomyopathy. The ability of anthracyclines to induce a chronic dose-dependent cardiomyopathy has been well documented. A number of approaches to abrogate this effect have been explored with varying degrees of success. These include the development of analogs of the parent ant

歡笑

金桌活畫面

褪色

andererseits verschwinden aber auch M?rkte, Intermedi?re bzw. Lieferanten werden durch effizientere Prozesse st?rker gebunden. Wo sich E-Commerce-Anwendungen etablieren, werden Wertsch?pfungsstrukturen ganzer Industrien ver?ndert. Die Transformationsprozesse sind durch vielf?ltige Interaktionen von

陳舊

John S. Holcenberg,Henry P. Wunelle Zahlungsmittel, wie beispielsweise die Rechnung und überweisung. Dies h?ngt mit mangelndem Vertrauen in den elektronischen Handel (E-Commerce) zusammen. Ursachen hierfür sind die Charakteristika und Effekte elektronischer Marktpl?tze, die gekennzeichnet sind durch Unvollkommenheiten und Komple