Titlebook: New Avenues to Efficient Chemical Synthesis; Emerging Technologie P.H. Seeberger,T. Blume Conference proceedings 2007 Springer-Verlag Berli

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Micro-Fluidic and Lab-on-a-Chip Technology,e, but also access a?range of unique characteristics, which are not achievable in conventional macro-scale systems. This chapter will discuss the unique properties of miniaturised systems based on micro-fluidic and Lab-on-a-Chip technology and consider how these may influence the overall performance

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Microreactors as New Tools for Drug Discovery and Development,me than is achievable with large-scale batch reactors. With monitoring of output flow, microreactors can be adjusted exquisitely to give enhanced and inherently safer protocols. Bulk production can be achieved through long run times or parallel reactors. However, microreactors can also be used advan

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Microchemical Systems for Discovery and Development,iphase catalytic systems to microsystems for multistep chemical synthesis. The latter systems involve extraction and gas–liquid separation processes designed to take advantage of the dominance of surface tension effects in microfluidic devices. Integration of physical sensors (e.g., for pressure, te

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An Integrated Approach to Developing Chemoenzymatic Processes at the Industrial Scale,protein expression, high-throughput screening, and enzyme evolution technologies. To truly impact chemical synthesis at the industrial scale, biotransformations and chemical research and development must be integrated to develop cost-effective and environmentally friendly solutions for drug manufact

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Solid-Phase Supported Synthesis: A Possibility for Rapid Scale-Up of Chemical Reactions,ed hydroxamic acid derivative as examples. These compounds were obtained through combinatorial chemistry and solution-phase synthesis was used in parallel to provide a?comparison. By applying highly loaded polystyrene-derived resins as the solid support, a?good ratio between the product and the star